Discovery of Molecular Interactions of the Human Melanocortin-4 Receptor (hMC4R) Asp189 (D189) Amino Acid with the Endogenous G-Protein-Coupled Receptor (GPCR) Antagonist Agouti-Related Protein (AGRP) Provides Insights to AGRP's Inverse Agonist Pharmacology at the hMC4R Article

cited authors

  • Ericson, Mark D.; Haslach, Erica M.; Schnell, Sathya M.; Freeman, Katie T.; Xiang, Zhimin M.; Portillo, Frederico P.; Speth, Robert; Litherland, Sally A.; Haskell-Luevano, Carrie

authors

Publication Date

  • February 3, 2021

webpage

published in

category

keywords

  • Macrocyclic peptide
  • inverse agonism
  • mutant hMC4R

start page

  • 542

end page

  • 556

volume

  • 12

issue

  • 3