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Korostenskaja, Milena PhD
Overview
overview
- Milena Korostenskaja, PhD, Neuroscientist, Head of the Functional Brain Mapping and Brain Computer Interface (FBMBCI) Laboratory at AdventHealth for Children, Orlando, FL, USA. Dr. Korostenskaja received her PhD working with magnetoencephalography (MEG) at BioMag Laboratory, Helsinki University Central Hospital, Finland and completed her post-doctoral training with MEG and electrocorticography (ECoG) techniques at the Department of Neurology, Cincinnati Children’s Hospital Medical Center, Ohio, USA. Founded in August 2011, the main goal of the current Dr. Korostenskaja’s FBM-BCI Laboratory at Florida Hospital is to assist the comprehensive epilepsy surgery program and improve outcomes of epilepsy surgery. The essential part of this program is localization of eloquent cortex (responsible for motor, sensory, language, and memory function) that must be maximally preserved while removing pathological epileptogenic substrate from the patients’ brain. Dr. Korostenskaja’s extensive training and expertise in utilizing ECoG and MEG techniques allowed her to implement innovative real-time ECoG-based functional mapping (real-time functional mapping – RTFM) for pre-surgical evaluation of epilepsy surgery patients. At the moment, Dr. Korostenskaja, with her colleagues and collaborators work on validation of RTFM against other functional mapping modalities, such as electrical cortical stimulation mapping (ESM), functional magnetic resonance imaging (fMRI) and MEG. The results of this research are highly promising and support clinical application of RTFM methodology for pre-surgical eloquent cortex localization. Moreover, Dr. Korostenskaja’s lead studies have demonstrated significant contribution of RTFM in decreasing post-surgical language morbidity.
research areas
Affiliation
Member of
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Clinical Program
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Research Department
Publications
Most Recent Publications
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2020Deep Learning Provides Exceptional Accuracy to ECoG-Based Functional Language Mapping for Epilepsy Surgery. FRONTIERS IN NEUROSCIENCE. 14.Full Text via DOI: 10.3389/fnins.2020.00409 PMID: 32435182
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2019A MEG Study on the Processing of Time and Quantity: Parietal Overlap but Functional Divergence. FRONTIERS IN PSYCHOLOGY. 10.Full Text via DOI: 10.3389/fpsyg.2019.00139 PMID: 30778314
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201840 Hz auditory steady-state response in schizophrenia: Sensitivity to stimulation type (clicks versus flutter amplitude-modulated tones). NEUROSCIENCE LETTERS. 662:152-157.Full Text via DOI: 10.1016/j.neulet.2017.10.025 PMID: 29051085
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2017Automatic Response Assessment in Regions of Language Cortex in Epilepsy Patients Using ECoG-based Functional Mapping and Machine Learning. 2017 IEEE INTERNATIONAL CONFERENCE ON SYSTEMS, MAN, AND CYBERNETICS (SMC). 519-524.
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2017Characterization of cortical motor function and imagery-related cortical activity: Potential application for prehabilitation. 2017 IEEE INTERNATIONAL CONFERENCE ON SYSTEMS, MAN, AND CYBERNETICS (SMC). 3014-3019.
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2017Passive Functional Mapping Guides Electrical Cortical Stimulation for Efficient Determination of Eloquent Cortex in Epilepsy Patients. 2017 39TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC). 4163-4166.PMID: 29060814
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2016Identification of Focal Epileptogenic Networks in Generalized Epilepsy Using Brain Functional Connectivity Analysis of Bilateral Intracranial EEG Signals. BRAIN TOPOGRAPHY. 29:728-737.Full Text via DOI: 10.1007/s10548-016-0493-3 PMID: 27142358
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2016Phase-locking index and power of 40-Hz auditory steady-state response are not related to major personality trait dimensions. EXPERIMENTAL BRAIN RESEARCH. 234:711-719.Full Text via DOI: 10.1007/s00221-015-4494-3 PMID: 26586270
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2016Multi-frequency localization of aberrant brain activity in autism spectrum disorder. BRAIN & DEVELOPMENT. 38:82-90.Full Text via DOI: 10.1016/j.braindev.2015.04.007 PMID: 25937458
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2015Advances of Electrophysiological Techniques in Pediatric Epilepsy. JOURNAL OF PEDIATRIC EPILEPSY. 137-138.Full Text via DOI: 10.1055/s-0035-1559811
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2015Electrocorticography-Based Real-Time Functional Mapping for Pediatric Epilepsy Surgery. JOURNAL OF PEDIATRIC EPILEPSY. 184-206.Full Text via DOI: 10.1055/s-0035-1563728
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2015High-Frequency Oscillations in Pediatric Epilepsy: Methodology and Clinical Application. JOURNAL OF PEDIATRIC EPILEPSY. 156-164.Full Text via DOI: 10.1055/s-0035-1563729
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2015CortiQ-based Real-Time Functional Mapping for Epilepsy Surgery. JOURNAL OF CLINICAL NEUROPHYSIOLOGY. 32:E12-E22.PMID: 25761260
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2015Bilateral intracranial EEG with corpus callosotomy may uncover seizure focus in nonlocalizing focal epilepsy. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY. 24:63-69.Full Text via DOI: 10.1016/j.seizure.2014.08.011 PMID: 25218113
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2015Physical Feature Encoding and Word Recognition Abilities Are Altered in Children with Intractable Epilepsy: Preliminary Neuromagnetic Evidence. BEHAVIOURAL NEUROLOGY. 2015.Full Text via DOI: 10.1155/2015/237436 PMID: 26146459
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2014Contributions of neuroimaging to understand childhood epileptic encephalopathies. JOURNAL OF PEDIATRIC EPILEPSY. 131-156.Full Text via DOI: 10.3233/PEP-14087
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2014Real-time functional mapping: potential tool for improving language outcome in pediatric epilepsy surgery. Case report. JOURNAL OF NEUROSURGERY-PEDIATRICS. 14:287-295.Full Text via DOI: 10.3171/2014.6.PEDS13477 PMID: 24995815
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2014Real-Time Functional Mapping With Electrocorticography in Pediatric Epilepsy: Comparison With fMRI and ESM Findings. CLINICAL EEG AND NEUROSCIENCE. 45:205-211.Full Text via DOI: 10.1177/1550059413492960 PMID: 24293161
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201440 Hz auditory steady-state response in females: When is it better to entrain?. ACTA NEUROBIOLOGIAE EXPERIMENTALIS. 74:91-97.PMID: 24718047
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2013Altered Cortical Activation in Adolescents With Acute Migraine: A Magnetoencephalography Study. JOURNAL OF PAIN. 14:1553-1563.Full Text via DOI: 10.1016/j.jpain.2013.04.009 PMID: 23792072
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2013REAL-TIME SOFTWARE FOR FUNCTIONAL MAPPING OF ELOQUENT CORTEX USING ELECTROCORTICOGRAPHY. BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK. 58.Full Text via DOI: 10.1515/bmt-2013-4176 PMID: 24042797
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2013REAL-TIME SOFTWARE FOR FUNCTIONAL MAPPING OF ELOQUENT CORTEX USING ELECTROCORTICOGRAPHY. BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK. 58.
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2013A SURGICAL METHOD FOR SAFELY IMPLANTING LARGE SUBDURAL ELECTRODE ARRAYS IN CHILDREN. EPILEPSIA. 287-288.
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2013Magnetoencephalography reveals altered auditory information processing in youth with obsessive-compulsive disorder. PSYCHIATRY RESEARCH-NEUROIMAGING. 212:132-140.Full Text via DOI: 10.1016/j.pscychresns.2012.11.011 PMID: 23545237
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2013NEUROPHYSIOLOGICAL MARKERS OF BRAIN'S ABILITY TO ENTRAIN AND TO DETECT CHANGE: METHODOLOGICAL CONSIDERATIONS. MEDICAL PHYSICS IN THE BALTIC STATES. 79-84.
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2013cortiQ - Clinical Software for Electrocorticographic Real-Time Functional Mapping of the Eloquent Cortex. 2013 35TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC). 6365-6368.PMID: 24111197
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2011Impaired Auditory Information Processing During Acute Migraine: A Magnetoencephalography Study. INTERNATIONAL JOURNAL OF NEUROSCIENCE. 121:355-365.Full Text via DOI: 10.3109/00207454.2011.560312 PMID: 21425948
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2010Neuromagnetic evidence of impaired cortical auditory processing in pediatric intractable epilepsy. EPILEPSY RESEARCH. 92:63-73.Full Text via DOI: 10.1016/j.eplepsyres.2010.08.008 PMID: 20863661
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2010Identification of Abnormal Neuromagnetic Signatures in the Motor Cortex of Adolescent Migraine. HEADACHE. 50:1005-1016.Full Text via DOI: 10.1111/j.1526-4610.2010.01674.x PMID: 20487034
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2009What do ERPs and ERFs Reveal About the Effect of Antipsychotic Treatment on Cognition in Schizophrenia?. CURRENT PHARMACEUTICAL DESIGN. 2573-2593.PMID: 19689329
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2009The effect of quetiapine on auditory P300 response in patients with schizoaffective disorder: Preliminary study. ANNALS OF CLINICAL PSYCHIATRY. 49-50.PMID: 19239832
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2008The effect of methylphenidate on auditory information processing in healthy volunteers: a combined EEG/MEG study. PSYCHOPHARMACOLOGY. 475-486.Full Text via DOI: 10.1007/s00213-007-1065-8 PMID: 18264697
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2007Effects of NMDA receptor antagonist memantine on mismatch negativity. BRAIN RESEARCH BULLETIN. 72:275-283.Full Text via DOI: 10.1016/j.brainresbull.2007.01.007 PMID: 17452287
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2006Effects of risperidone on auditory information processing in neuroleptic-naive patients with schizophrenia spectrum disorders. ACTA NEUROBIOLOGIAE EXPERIMENTALIS. 66:139-144.PMID: 16886724
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2005Effects of olanzapine on auditory P300 and mismatch negativity (MMN) in schizophrenia spectrum disorders. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 543-548.Full Text via DOI: 10.1016/j.pnpbp.2005.01.019 PMID: 15866356
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2003Evaluation of new MMN parameters in schizophrenia. ACTA NEUROBIOLOGIAE EXPERIMENTALIS. 63:383-388.PMID: 15053262
Background
Full Name
- Milena PhD Korostenskaja
Education
- Helsinki University Central Hospital, Finland
Contact
primary email
- Research.Institute@AdventHealth.com