In the United States, acute pancreatitis is the most common cause of hospitalization related to GI disease.(1) The incidence of acute pancreatitis is between 9.8 and 32 per 100,000, with a 30- to 90-day mortality rate of 7%.(2,3) Pancreatic pseudocysts are a well-known adverse event of acute and chronic pancreatitis.(4) Pseudocysts develop in 6% to 34% of cases of acute pancreatitis, but only a proportion are symptomatic, and many resolve spontaneously.(5-7) Endoscopic drainage has become standard treatment at many centers, with similar efficacy, shorter hospital stays, fewer adverse events, better physical and mental health outcomes, and greater cost effectiveness compared with surgical cystogastrostomy.(8,9) It is therefore considered as first-line treatment. This review highlights the techniques used for endoscopic management of pseudocysts. It provides background into the current definition and the indications for and timing of endoscopic intervention, and it describes the various drainage techniques, adverse events, recommended before-and after-procedure management, and areas of uncertainty.