Pulmonary vein isolation using "contact force" ablation: The effect on dormant conduction and long-term freedom from recurrent atrial fibrillation-A prospective study Article

International Collaboration

cited authors

  • Andrade, Jason G., Monir, George, Pollak, Scott J., Khairy, Paul, Dubuc, Marc, Roy, Denis, Talajic, Mario, Deyell, Marc, Rivard, Lena, Thibault, Bernard, Guerra, Peter G., Nattel, Stanley, Macle, Laurent

abstract

  • BACKGROUND Atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI) is associated with PV to Left atrium reconduction. Effective lesion creation necessitates adequate contact force between the ablation catheter and myocardium. OBJECTIVE The purpose of this study was to study the utility of contact force guided ablation on immediate and long-term outcomes. METHODS Seventy-five patients with highly symptomatic paroxysmal AF underwent wide circumferential PVI using an irrigated-tip radiofrequency catheter. In 25 patients, ablation was guided by real-time contact force measurements (CF group; SmartTouch, Biosense Webster). A control group of 50 patients underwent PVI using a standard nonforce sensing catheter (standard group; ThermoCool, Biosense Webster). After PVI, all patients underwent adenosine testing to unmask dormant conduction. Patients were followed up at 3, 6, and 12 months and by transtelephonic monitoring as well. RESULTS Dormant conduction was unmasked and subsequently eliminated in 4 PV pairs (8%; 16% of patients) in the CF group and 35 PV pairs (35%; 52% of patients) in the standard group (P = .0004 per PV pair; P = .0029 per patient). The single-procedure, off antiarrhythmic drug freedom from recurrent atrial arrhythmias at 1 year was 88% in the CF group vs 66% in the standard group (P = .047). Procedure duration and fluoroscopy time were significantly Longer in the CF group (P = .0038 and P = .0001, respectively). CONCLUSION The use of real-time contact force guidance results in a significant reduction in the prevalence of dormant conduction with improved long-term freedom from recurrent arrhythmias. The utility of a contact force guided approach requires evaluation in a Long-term prospective randomized study.

authors

Publication Date

  • November 1, 2014

webpage

published in

category

start page

  • 1919

end page

  • 1924

volume

  • 11

issue

  • 11

WoS Citations

  • 60

WoS References

  • 30