Sultana, N., Pikaart, D. P., Ahmad, S., DeNardis, S. A., Finkler, N. J.
abstract
Purpose: Leiomyosarcoma is a rare neoplasm. There is paucity of literature in regards to paraovarian leiomyosarcoma with metastases to the scalp. We present a 72-year-old woman with metastases to the scalp from a primary paraovarian high grade leiomyosarcoma. Methods and Results: The patient underwent a total abdominal hysterectomy, pelvic and aortic lymphadenectomy, excision of Meckel's diverticulum, and radical pelvic tumor debulking with sigmoid colectomy and end-to-end anastomosis and six cycles of taxotere/carboplatin. She presented 18 months later with metastatic high-grade leiomyosarcoma to the scalp. The lesions were excised and she is now receiving palliative taxotere and gemcitabin. Conclusion: High-grade leiomyosarcoma is known for its resistance to chemotherapy, radiation therapy, and propensity for hematological dissemination with an overall poor prognosis.