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Gonzalez-Peralta, Regino, MD
Overview
overview
- Regino Gonzalez-Peralta, MD, is a board-certified pediatric gastroenterologist with additional board certification in pediatric transplant hepatology. Prior to joining AdventHealth Medical Group, he served as a tenured pediatrics professor, assistant dean and director of pediatric hepatology at the University of Florida and concurrently served as a pediatric hepatologist at Arnold Palmer Hospital for Children. A native of Cuba, Dr. Gonzalez-Peralta grew up in Miami and attended Cornell University before pursuing his medical degree at the Universidad Central del Este (Dominican Republic). He undertook his pediatrics residency at Cook County Hospital in Chicago, and continued as Senior Resident and Co-Chief Resident at the University of Florida before being selected for a prestigious fellowship in pediatric gastroenterology. His clinical and research interests include childhood HBV and HCV infection, pediatric liver transplant, Wilson disease, alpha 1 antitrypsin deficiency, pediatric hepatology and clinical trials.
Affiliation
Member of
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Clinical Program
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Research Department
Publications
Most Recent Publications
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2024Maralixibat in progressive familial intrahepatic cholestasis (MARCH-PFIC): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial. LANCET GASTROENTEROLOGY & HEPATOLOGY. 9.Full Text via DOI: 10.1016/S2468-1253(24)00080-3 PMID: 38723644
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2024Sofosbuvir-velpatasvir in children 3-17 years old with hepatitis C virus infection. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 78:1342-1354.Full Text via DOI: 10.1002/jpn3.12045 PMID: 38644678
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2024ESPGHAN recommendations on treatment of chronic hepatitis C virus infection in adolescents and children including those living in resource-limited settings. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 78:957-972.Full Text via DOI: 10.1002/jpn3.12160 PMID: 38369891
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2024Real-world experience of maralixibat in Alagille syndrome: Novel findings outside of clinical trials. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 78:506-513.Full Text via DOI: 10.1002/jpn3.12101 PMID: 38334237
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2024Impact of early immunosuppression on pediatric liver transplant outcomes within 1 year. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION.Full Text via DOI: 10.1002/jpn3.12112
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2023MONITORING MAINTENANCE THERAPY WITH D-PENICILLAMINE FOR WILSON'S DISEASE: LESSONS FROM SCREENING FOR A RANDOMIZED TRIAL. GUT. A25-A26.Full Text via DOI: 10.1136/gutjnl-2023-BASL.37
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2023Analysis of safety in maralixibat-treated participants with progressive familial intrahepatic cholestasis: data from MARCH-PFIC. JOURNAL OF HEPATOLOGY. S387-S388.
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2023Procedure Costs Associated with Management of Biliary Strictures in Pediatric Liver Transplant Recipients in the Society of Pediatric Liver Transplant (SPLIT) Registry. AMERICAN JOURNAL OF TRANSPLANTATION. S1013-S1013.
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2023Wilson disease: a summary of the updated AASLD Practice Guidance. HEPATOLOGY COMMUNICATIONS.Full Text via DOI: 10.1097/HC9.0000000000000150 PMID: 37184530
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2023Elbasvir/grazoprevir in children aged 3-18 years with chronic HCV genotype 1 or 4 infection: a pharmacokinetic modeling study. HEPATOLOGY COMMUNICATIONS. 7.Full Text via DOI: 10.1097/HC9.0000000000000031 PMID: 36790337
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2023Major Depressive Disorder in an International Multisite Wilson Disease Registry. JOURNAL OF THE ACADEMY OF CONSULTATION-LIAISON PSYCHIATRY. 64:106-117.PMID: 36521682
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2022Feasibility of using a patient-reported outcome measure into clinical practice following pediatric liver transplantation: The Starzl Network experience. PEDIATRIC TRANSPLANTATION.Full Text via DOI: 10.1111/petr.14409 PMID: 36272132
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2022
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2022REAL-WORLD SAFETY EXPERIENCE IN PATIENTS WITH ALAGILLE SYNDROME TREATED WITH MARALIXIBAT. HEPATOLOGY. S1528-S1528.
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2022North American Biliary Stricture Management Strategies in Children After Liver Transplantation: A Multicenter Analysis From the Society of Pediatric Liver Transplantation (SPLIT) Registry. LIVER TRANSPLANTATION.Full Text via DOI: 10.1002/lt.26379 PMID: 34837468
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2021
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2021The Effect of Mental Health, Neurological Disease, and Liver Disease on Quality of Life in Patients With Wilson Disease. JOURNAL OF THE ACADEMY OF CONSULTATION-LIAISON PSYCHIATRY. 62:528-537.PMID: 34044196
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2021Pharmacokinetics, Safety, and Efficacy of Glecaprevir/Pibrentasvir in Children With Chronic HCV: Part 2 of the DORA Study. HEPATOLOGY. 74:19-27.Full Text via DOI: 10.1002/hep.31841 PMID: 33811356
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2021A Learning Health System for Pediatric Liver Transplant: The Starzl Network for Excellence in Pediatric Transplantation. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 72:417-424.Full Text via DOI: 10.1097/MPG.0000000000002974 PMID: 33560758
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2020LONG TERM FOLLOW-UP OF SAFETY AND EFFICACY OF SOFOSBUVIR-BASED HCV DAAS IN PEDIATRIC PATIENTS. HEPATOLOGY. 565A-565A.
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2020
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2020EFFECT OF LIVER DISEASE, NEUROLOGICAL DISEASE AND MENTAL HEALTH ISSUES ON QUALITY OF LIFE IN PATIENTS WITH WILSON DISEASE. GUT. A13-A13.Full Text via DOI: 10.1136/gutjnl-2020-BASL.23
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2020Hepatitis C in 2020: A North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Position Paper. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 71:407-417.Full Text via DOI: 10.1097/MPG.0000000000002814 PMID: 32826718
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2020Bipolar disorder in patients with Wilson disease. JOURNAL OF PSYCHOSOMATIC RESEARCH.Full Text via DOI: 10.1016/j.jpsychores.2020.110055
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2020Comparison of Recommendations for Treatment of Chronic Hepatitis C Virus Infection in Children and Adolescents: A Position Paper of the Federation of International Societies of Pediatric Gastroenterology, Hepatology, and Nutrition. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 70:711-717.Full Text via DOI: 10.1097/MPG.0000000000002710 PMID: 32205770
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2019Sofosbuvir and Ribavirin Therapy for Children Aged 3 to < 12 Years With Hepatitis C Virus Genotype 2 or 3 Infection. HEPATOLOGY. 71:31-43.Full Text via DOI: 10.1002/hep.30821 PMID: 31222783
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2019A learning health network for pediatric liver transplantation: Inaugural meeting report from the Starzl Network for Excellence in Pediatric Transplantation. PEDIATRIC TRANSPLANTATION. 23.Full Text via DOI: 10.1111/petr.13528 PMID: 31328841
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2019Development and Implementation of a Pediatric Transplant Consortium.. AMERICAN JOURNAL OF TRANSPLANTATION. 1003-1003.
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2018Safety and Efficacy of Ledipasvir-Sofosbuvir With or Without Ribavirin for Chronic Hepatitis C in Children Ages 6-11. HEPATOLOGY. 68:2158-2166.Full Text via DOI: 10.1002/hep.30123 PMID: 30070726
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2018Ombitasvir/Paritaprevir/Ritonavir With or Without Dasabuvir and With or Without Ribavirin for Adolescents With HCV Genotype 1 or 4. HEPATOLOGY COMMUNICATIONS. 2:1311-1319.Full Text via DOI: 10.1002/hep4.1250 PMID: 30411078
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2018Severe Direct Hyperbilirubinemia as a Consequence of Right Heart Failure in Congenital Heart Disease. WORLD JOURNAL FOR PEDIATRIC AND CONGENITAL HEART SURGERY. 9:470-474.Full Text via DOI: 10.1177/2150135116640786 PMID: 27154793
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2018Quality of life in adolescents with hepatitis C treated with sofosbuvir and ribavirin. JOURNAL OF VIRAL HEPATITIS. 25:354-362.Full Text via DOI: 10.1111/jvh.12830 PMID: 29193603
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2018SCLEROSING CHOLANGITIS IN KABUKI SYNDROME: AN UNUSUAL COMPLICATION OF A RARE DISORDER. JOURNAL OF INVESTIGATIVE MEDICINE. 483-484.Full Text via DOI: 10.1136/jim-2017-000697.325
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2018Extracellular Calcium Dictates Onset, Severity, and Recovery of Diarrhea in a Child with Immune-Mediated Enteropathy. FRONTIERS IN PEDIATRICS. 6.Full Text via DOI: 10.3389/fped.2018.00007 PMID: 29435439
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2017Mucinous Cystadenoma: A Rare Hepatic Tumor in a Child. FRONTIERS IN PEDIATRICS. 5.Full Text via DOI: 10.3389/fped.2017.00215 PMID: 29062832
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2017Sofosbuvir and Ribavirin in Adolescents 12-17 Years Old With Hepatitis C Virus Genotype 2 or 3 Infection. HEPATOLOGY. 66:1102-1110.Full Text via DOI: 10.1002/hep.29278 PMID: 28543053
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2017The Safety and Effectiveness of Ledipasvir-Sofosbuvir in Adolescents 12-17 Years Old With Hepatitis C Virus Genotype 1 Infection. HEPATOLOGY. 66:371-378.Full Text via DOI: 10.1002/hep.28995 PMID: 27997679
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2017The Challenge of Treating Children With Hepatitis C Virus Infection. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 64:851-854.Full Text via DOI: 10.1097/MPG.0000000000001589 PMID: 28362694
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2016Viral Hepatitis in Children: A Through E. PEDIATRIC ANNALS. 45:E420-E426.Full Text via DOI: 10.3928/19382359-20161114-01 PMID: 27975110
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2016Transmission of Balamuthia mandrillaris by Organ Transplantation. CLINICAL INFECTIOUS DISEASES. 63:878-888.Full Text via DOI: 10.1093/cid/ciw422 PMID: 27358357
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2016Autoimmune Hepatitis in Pregnancy: Hematological Perturbation and Management Dilemma A Case Report. JOURNAL OF REPRODUCTIVE MEDICINE. 61:524-526.PMID: 30383957
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2016Durability of Response in Children Treated With Pegylated Interferon alfa-2a +/- Ribavirin for Chronic Hepatitis C. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 62:93-96.Full Text via DOI: 10.1097/MPG.0000000000000929 PMID: 26284539
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2015Correlates of Adiponectin in Hepatitis C-Infected Children: The Importance of Body Mass Index. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 60:165-170.Full Text via DOI: 10.1097/MPG.0000000000000604 PMID: 25313851
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2014Long-Term Growth Outcomes in Children Treated for Chronic Hepatitis C. JOURNAL OF PEDIATRICS. 1252-1254.Full Text via DOI: 10.1016/j.jpeds.2014.08.010 PMID: 25241178
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2014Simultaneous liver-pancreas transplantation for cystic fibrosis-related liver disease: A multicenter experience. JOURNAL OF CYSTIC FIBROSIS. 13:471-477.Full Text via DOI: 10.1016/j.jcf.2013.12.010 PMID: 24440180
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2013Evaluating Progression of Liver Disease From Repeat Liver Biopsies in Children With Chronic Hepatitis C: A Retrospective Study. HEPATOLOGY. 58:1580-1586.Full Text via DOI: 10.1002/hep.26519 PMID: 23703847
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2013Calcium Ameliorates Diarrhea in Immunocompromised Children. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 56:641-644.Full Text via DOI: 10.1097/MPG.0b013e3182868946 PMID: 23343935
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2013Autoantibodies and Autoimmune Disease During Treatment of Children With Chronic Hepatitis C. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 56:304-310.Full Text via DOI: 10.1097/MPG.0b013e3182774cae PMID: 23439301
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2012Expected and Actual Case Ascertainment and Treatment Rates for Children Infected with Hepatitis C in Florida and the United States: Epidemiologic Evidence from Statewide and Nationwide Surveys. JOURNAL OF PEDIATRICS. 161:915-921.Full Text via DOI: 10.1016/j.jpeds.2012.05.002 PMID: 22765955
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2012Pegylated interferon for chronic hepatitis C in children affects growth and body composition: Results from the pediatric study of hepatitis C (PEDS-C) trial. HEPATOLOGY. 56:523-531.Full Text via DOI: 10.1002/hep.25690 PMID: 22383118
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2012NASPGHAN Practice Guidelines: Diagnosis and Management of Hepatitis C Infection in Infants, Children, and Adolescents. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 54:838-855.Full Text via DOI: 10.1097/MPG.0b013e318258328d PMID: 22487950
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2011Liver transplantation in a 7-month-old girl with Caroli's disease. JOURNAL OF PEDIATRIC SURGERY. 46:1638-1641.Full Text via DOI: 10.1016/j.jpedsurg.2011.04.011 PMID: 21843735
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2011The Combination of Ribavirin and Peginterferon Is Superior to Peginterferon and Placebo for Children and Adolescents With Chronic Hepatitis C. GASTROENTEROLOGY. 140:450-U148.Full Text via DOI: 10.1053/j.gastro.2010.10.047 PMID: 21036173
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2009Hepatocellular carcinoma in a 10-month-old biliary atresia child. PEDIATRIC TRANSPLANTATION. 13:1048-1049.Full Text via DOI: 10.1111/j.1399-3046.2008.01094.x PMID: 19032418
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2009Asymptomatic presentation of mesalamine-induced lung injury in an adolescent with Crohn disease.. BMJ CASE REPORTS.Full Text via DOI: 10.1136/bcr.09.2008.0908 PMID: 21686567
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2008Growth hormone therapy improves growth in children with cystic fibrosis related liver disease. JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM. 21:793-797.PMID: 18825880
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2008Pathology of chronic hepatitis C in children: Liver biopsy findings in the Peds-C trial. HEPATOLOGY. 47:836-843.Full Text via DOI: 10.1002/hep.22094 PMID: 18167062
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2007Liver transplantation in children with sickle-cell disease. LIVER TRANSPLANTATION. 13:505-508.Full Text via DOI: 10.1002/lt.20999 PMID: 17394147
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2007Liver transplantation in very small infants. PEDIATRIC TRANSPLANTATION. 11:66-72.Full Text via DOI: 10.1111/j.1399-3046.2006.00610.x PMID: 17239125
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2005Developmental considerations in the context of pediatric transplantation.. Annals of transplantation. 13-6.PMID: 15926745
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2004Polycythemia vera in a child following treatment for acute lymphoblastic leukemia. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY. 26:315-319.PMID: 15111786
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2001Graft survival in pediatric liver transplantation. JOURNAL OF PEDIATRIC SURGERY. 36:1205-1209.Full Text via DOI: 10.1053/jpsu.2001.25763 PMID: 11479857
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2001Antiepileptic hypersensitivity syndrome in children. ANNALS OF PHARMACOTHERAPY. 35:533-538.PMID: 11346057
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1997Transforming growth factor-beta(1) in chronic hepatitis C. JOURNAL OF VIRAL HEPATITIS. 4:29-35.PMID: 9031062
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1994PATHOGENETIC MECHANISMS OF HEPATOCELLULAR DAMAGE IN CHRONIC HEPATITIS-C VIRUS-INFECTION. JOURNAL OF HEPATOLOGY. 255-259.PMID: 7989719
Research
principal investigator on
Background
Full Name
- Regino Gonzalez-Peralta, MD
Education
- Universidad Central Del Este
Residency
- John H. Stroger, Jr, Hospital of Cook County - Graduate Education Cook County Health
Fellowship
- University of Florida University of Florida - College of Medicine
Board Certification
- American Board of Pediatrics
Contact
primary email
- Research.Institute@AdventHealth.com