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Whytock, Katie, PhD, MSc

overview

  • Dr. Whytock’s research focuses on defining the molecular mechanisms underpinning skeletal muscle insulin resistance to identify therapeutic strategies to improve insulin sensitivity. Insulin resistance is a precursor to type 2 diabetes and cardiovascular disease and disproportionately affects older people, people with obesity, and individuals with metabolic syndromes such as PCOS. Her lab employs an integrative bedside-to-bench-to-bioinformatics and back approach that identifies novel biomarkers related to gold-standard metabolic phenotyping measures such as skeletal muscle insulin sensitivity quantified by stable isotope labelled hyperinsulinemic-euglycemic clamp. Skeletal muscle is composed of a multitude of different cell types that each impact insulin sensitivity differently and can respond to interventions heterogeneously. At the bench Dr. Whytock employs single cell and spatial transcriptomics techniques to identify cell-specific dysregulated profiles and targets. Exercise training remains a powerful tool to improve metabolic health however the majority of the adult population do not meet current physical activity guidelines due to varying reasons. Dr. Whytock’s goal is to identify alternative or complementary strategies to exercise training that can be used to improve insulin sensitivity. Dr. Whytock joined TRI in April 2019 as a post-doc investigating the molecular regulation of adipose tissue. Prior to joining TRI she completed her PhD from Liverpool John Moores University focusing on skeletal muscle metabolism and health.

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Full Name

  • Katie Whytock, PhD

primary email

  • Research.Institute@AdventHealth.com