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Varela, Juan Carlos, PhD, MD
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research areas
Publications
Most Recent Publications
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2022Evaluation of different pharmacokinetically guided IV busulfan exposure ranges on adult patient outcomes after hematopoietic stem cell transplantation. ANNALS OF HEMATOLOGY.Full Text via DOI: 10.1007/s00277-022-05042-z PMID: 36462061
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2022Cryopreserved versus fresh peripheral blood allogeneic stem cell transplantation outcomes in patients receiving post-transplant cyclophosphamide for graft-versus-host prophylaxis during the COVID-19 pandemic: a single center experience. INTERNATIONAL JOURNAL OF HEMATOLOGY.Full Text via DOI: 10.1007/s12185-022-03493-8 PMID: 36378406
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2022Results from Outreach: A Phase 2 Study of Lisocabtagene Maraleucel (Liso-cel) Administered As Outpatient (Outpt) or Inpatient (Inpt) Treatment in the Community/Nonuniversity Setting in Patients (Pts) with Relapsed or Refractory (R/R) Large B-Cell Lymphoma (LBCL). BLOOD. 10416-10418.Full Text via DOI: 10.1182/blood-2022-159595
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2021Mutational profiling of myeloid neoplasms associated genes may aid the diagnosis of acute myeloid leukemia with myelodysplasia-related changes. LEUKEMIA RESEARCH. 110.Full Text via DOI: 10.1016/j.leukres.2021.106701 PMID: 34481124
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2021Comparison of Myeloablative versus Reduced-Intensity Conditioning Regimens in Allogeneic Stem Cell Transplantation Recipients with Acute Myelogenous Leukemia with Measurable Residual Disease-Negative Disease at the Time of Transplantation: A Retrospective Cohort Study. TRANSPLANTATION AND CELLULAR THERAPY. 27.Full Text via DOI: 10.1016/j.jtct.2021.04.017 PMID: 33951497
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2021Impact of Next-Generation Sequencing Cell-free Pathogen DNA Test on Antimicrobial Management in Adults with Hematological Malignancies and Transplant Recipients with Suspected Infections. TRANSPLANTATION AND CELLULAR THERAPY. 27.Full Text via DOI: 10.1016/j.jtct.2021.02.025 PMID: 33849818
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2020Conditioning regimen intensity and low-dose azacitidine maintenance after allogeneic hematopoietic cell transplantation for acute myeloid leukemia. LEUKEMIA & LYMPHOMA. 61:2839-2849.Full Text via DOI: 10.1080/10428194.2020.1789630 PMID: 32650686
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2020Targeting the Complement Alternative Pathway Permits Graft Versus Leukemia Activity while Preventing Graft Versus Host Disease. CLINICAL CANCER RESEARCH. 26:3481-3490.Full Text via DOI: 10.1158/1078-0432.CCR-19-1717 PMID: 31919135
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2020Role of Post-Allogeneic Hematopoietic Stem Cell Transplantation Low-Dose Azacitidine for Prevention of Relapse in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome: A Retrospective Analysis. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. S126-S127.
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2020Ruxolitinib Is a Safe and Effective Therapeutic Option for Management of Chronic Gvhd - a Single Center Experience. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. S193-S194.
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2019Eltrombopag for Treating Thrombocytopenia after Allogeneic Stem Cell Transplantation. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. 25:1320-1324.Full Text via DOI: 10.1016/j.bbmt.2019.01.027 PMID: 30710685
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2019Increased bone marrow CD56(bright) natural killer cells at 30 days after allogeneic stem cell transplantation associated with adverse patient outcome. BONE MARROW TRANSPLANTATION. 924-927.Full Text via DOI: 10.1038/s41409-018-0407-y PMID: 30563982
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2019Aggressive Leukemic Non-Nodal Mantle Cell Lymphoma With P53 Gene Rearrangement/Mutation is Highly Responsive to Rituximab/Ibrutinib Combination Therapy. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 19:E93-E97.Full Text via DOI: 10.1016/j.clml.2018.11.007 PMID: 30559058
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2018Addition of Cladribine: Improving Standard of Care in Newly Diagnosed Acute Myeloid Leukemia. BLOOD.Full Text via DOI: 10.1182/blood-2018-99-120285
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2018Correction: Antigen-specific T cell Redirectors: a nanoparticle based approach for redirecting T cells.. ONCOTARGET. 32401.Full Text via DOI: 10.18632/oncotarget.26018 PMID: 30190796
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2017beta-catenin and PI3K delta inhibition expands precursor Th17 cells with heightened stemness and antitumor activity. JCI INSIGHT. 2.Full Text via DOI: 10.1172/jci.insight.90547 PMID: 28422756
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2017The Basics of Artificial Antigen Presenting Cells in T Cell-Based Cancer Immunotherapies.. Journal of immunology research and therapy. 68-79.PMID: 28825053
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2016Antigen-specific T cell Redirectors: a nanoparticle based approach for redirecting T cells. ONCOTARGET. 7:68503-68512.Full Text via DOI: 10.18632/oncotarget.11785 PMID: 27602488
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2015Enrichment and Expansion with Nanoscale Artificial Antigen Presenting Cells for Adoptive Immunotherapy. ACS NANO. 9:6861-6871.Full Text via DOI: 10.1021/acsnano.5b02829 PMID: 26171764
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2015Complement An Overview for the Clinician. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA. 29:409-+.Full Text via DOI: 10.1016/j.hoc.2015.02.001 PMID: 26043382
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2015CD47 Enhances In Vivo Functionality of Artificial Antigen-Presenting Cells. CLINICAL CANCER RESEARCH. 21:2075-2083.Full Text via DOI: 10.1158/1078-0432.CCR-14-2696 PMID: 25593301
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2015Adoptive T Cell Immunotherapy for Cancer. RAMBAM MAIMONIDES MEDICAL JOURNAL. 6.Full Text via DOI: 10.5041/RMMJ.10179 PMID: 25717386
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2014Complement blockade with a C1 esterase inhibitor in paroxysmal nocturnal hemoglobinuria. EXPERIMENTAL HEMATOLOGY. 42:857-861.Full Text via DOI: 10.1016/j.exphem.2014.06.007 PMID: 25034232
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2014Mechanical properties of a new thermoplastic polymer orthodontic archwire. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS. 42:1-6.Full Text via DOI: 10.1016/j.msec.2014.05.008 PMID: 25063084
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2013Paroxysmal nocturnal hemoglobinuria and the age of therapeutic complement inhibition. EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 1113-1124.Full Text via DOI: 10.1586/1744666X.2013.842896 PMID: 24168416
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2011Excision of Esophageal Duplication Cysts with Robotic-Assisted Thoracoscopic Surgery. JSLS : Journal of the Society of Laparoendoscopic Surgeons. 15:244-247.Full Text via DOI: 10.4293/108680811X13071180406961 PMID: 21902985
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2010Alterations in gene expression of complement components in chronic rhinosinusitis. AMERICAN JOURNAL OF RHINOLOGY & ALLERGY. 24:21-25.Full Text via DOI: 10.2500/ajra.2010.24.3399 PMID: 20109314
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2009Complement-Dependent Inflammation and Injury in a Murine Model of Brain Dead Donor Hearts. CIRCULATION RESEARCH. 105:1094-U112.Full Text via DOI: 10.1161/CIRCRESAHA.109.194977 PMID: 19815824
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2008Upregulated expression of complement inhibitory proteins on bladder cancer cells and anti-MUC1 antibody immune selection. INTERNATIONAL JOURNAL OF CANCER. 123:1357-1363.Full Text via DOI: 10.1002/ijc.23676 PMID: 18561323
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2008Modulation of protective T cell immunity by complement inhibitor expression on tumor cells. CANCER RESEARCH. 68:6734-6742.Full Text via DOI: 10.1158/0008-5472.CAN-08-0502 PMID: 18701498
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2007Enhancement of antibody-dependent mechanisms of tumor cell lysis by a targeted activator of complement. CANCER RESEARCH. 67:9535-9541.Full Text via DOI: 10.1158/0008-5472.CAN-07-1690 PMID: 17909064
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2006Complement-dependent P-selectin expression and injury following ischemic stroke. JOURNAL OF IMMUNOLOGY. 177:7266-7274.PMID: 17082645
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2005An innovative microarray strategy identities informative molecular markers for the detection of micrometastatic breast cancer. CLINICAL CANCER RESEARCH. 11:3697-3704.PMID: 15897566
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2004Temporal patterns of gene expression in murine cutaneous burn wound healing. PHYSIOLOGICAL GENOMICS. 16:341-348.Full Text via DOI: 10.1152/physiolgenomics.00101.2003 PMID: 14966252
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2003Analysis of gene expression patterns in human postburn hypertrophic scars. JOURNAL OF BURN CARE & REHABILITATION. 24:371-377.Full Text via DOI: 10.1097/01.BCR.0000095508.96754.E0 PMID: 14610421
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2003Microarray analysis of A549 cells infected with rabbitpox virus (RPV): a comparison of wild-type RPV and RPV deleted for the host range gene, SPI-1. VIROLOGY. 315:322-334.Full Text via DOI: 10.1016/S0042-6822(03)00532-4 PMID: 14585335
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2003Connective tissue growth factor expression and action in human corneal fibroblast cultures and rat corneas after photorefractive keratectomy. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 44:1879-1887.Full Text via DOI: 10.1167/iovs.02-0860 PMID: 12714619
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2002Microarray analysis of gene expression patterns during healing of rat corneas after excimer laser photorefractive keratectomy. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 43:1772-1782.PMID: 12036978
Background
Full Name
- Juan Carlos Varela, PhD