Newton, Herbert Bruce, MD, FAAN

2022

THE GENOMIC, TRANSCRIPTOMIC, AND EPIGENOMIC LANDSCAPE OF ISOCITRATE DEHYDROGENASE WILD TYPE GLIOBLASTOMA ACROSS THE AGE CONTINUUM. NEURO-ONCOLOGY. 13-14.

2022

Molecular alterations associated with improved outcome in patients with glioblastoma treated with Tumor-Treating Fields. NEURO-ONCOLOGY ADVANCES. 4.

Full Text via DOI: 10.1093/noajnl/vdac096 PMID: 35821680

2021

A phase 1 trial of the histone deacetylase inhibitor AR-42 in patients with neurofibromatosis type 2-associated tumors and advanced solid malignancies. CANCER CHEMOTHERAPY AND PHARMACOLOGY. 87:599-611.

Full Text via DOI: 10.1007/s00280-020-04229-3 PMID: 33492438

2020

BRAF MUTATION IS AN EARLY EVENT IN THE EVOLUTION OF A SUBSET OF GLIOBLASTOMAS AND IS ASSOCIATED WITH INCREASED PD-L1 EXPRESSION. NEURO-ONCOLOGY. 5-5.

2020

Molecular features of gliomas with high tumor mutational burden.. JOURNAL OF CLINICAL ONCOLOGY.

2019

Successful Intrathecal Rituximab Administration in Refractory Nonteratoma Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Case Report. JOURNAL OF NEUROSCIENCE NURSING. 51:194-197.

Full Text via DOI: 10.1097/JNN.0000000000000450 PMID: 31180943

2019

Miscellaneous chemotherapy approaches to oligodendroglial tumors. OLIGODENDROGLIOMA: CLINICAL PRESENTATION, PATHOLOGY, MOLECULAR BIOLOGY, IMAGING, AND TREATMENT. 353-357.

Full Text via DOI: 10.1016/B978-0-12-813158-9.00030-X

2019

Oligodendrogliomas-Atypical clinical presentations. OLIGODENDROGLIOMA: CLINICAL PRESENTATION, PATHOLOGY, MOLECULAR BIOLOGY, IMAGING, AND TREATMENT. 23-37.

Full Text via DOI: 10.1016/B978-0-12-813158-9.00003-7

2019

Temozolomide chemotherapy for oligodendroglial tumors. OLIGODENDROGLIOMA: CLINICAL PRESENTATION, PATHOLOGY, MOLECULAR BIOLOGY, IMAGING, AND TREATMENT. 341-351.

Full Text via DOI: 10.1016/B978-0-12-813158-9.00029-3

2016

Phase II multicenter study of gene-mediated cytotoxic immunotherapy as adjuvant to surgical resection for newly diagnosed malignant glioma. NEURO-ONCOLOGY. 18:1137-1145.

Full Text via DOI: 10.1093/neuonc/now002 PMID: 26843484

2015

Central Nervous System Cancers, Version 1.2015 Featured Updates to the NCCN Guidelines. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK. 13:1191-1202.

PMID: 26483059

2015

Survival outcomes and safety of carmustine wafers in the treatment of high-grade gliomas: a meta-analysis. JOURNAL OF NEURO-ONCOLOGY. 122:367-382.

Full Text via DOI: 10.1007/s11060-015-1724-2 PMID: 25630625

2015

Efficacy and patient-reported outcomes with dose-intense temozolomide in patients with newly diagnosed pure and mixed anaplastic oligodendroglioma: a phase II multicenter study. JOURNAL OF NEURO-ONCOLOGY. 122:111-119.

Full Text via DOI: 10.1007/s11060-014-1684-y PMID: 25534576

2014

Central Nervous System Cancers, Version 2.2014 Featured Updates to the NCCN Guidelines. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK. 12:1517-1523.

PMID: 25361798

2014

J Neuropathol Exp Neurol. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. 474-476.

Full Text via DOI: 10.1097/NEN.0000000000000061 PMID: 24709681

2014

Hypofractionated intensity modulated radiotherapy with temozolomide in newly diagnosed glioblastoma multiforme. JOURNAL OF CLINICAL NEUROSCIENCE. 21:633-637.

Full Text via DOI: 10.1016/j.jocn.2013.09.005 PMID: 24380758

2014

Neurosarcoidosis: Clinical Review of a Disorder With Challenging Inpatient Presentations and Diagnostic Considerations. NEUROHOSPITALIST. 94-101.

Full Text via DOI: 10.1177/1941874413519447 PMID: 24707339

2013

Central Nervous System Cancers Clinical Practice Guidelines in Oncology. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK. 1114-1151.

PMID: 24029126

2012

"Tumoral Pseudoblush" Identified within Gliomas at High-Spatial-Resolution Ultrahigh-Field-Strength Gradient-Echo MR Imaging Corresponds to Microvascularity at Stereotactic Biopsy. RADIOLOGY. 264:210-217.

Full Text via DOI: 10.1148/radiol.12110799 PMID: 22627600

2012

Bevacizumab for glioblastoma refractory to vascular endothelial growth factor receptor inhibitors. JOURNAL OF NEURO-ONCOLOGY. 107:407-411.

Full Text via DOI: 10.1007/s11060-011-0768-1 PMID: 22203237

2012

Ependymomas, neuronal and mixed neuronal-glial tumors, dysembroblastic neuroepithelial tumors, pleomorphic xanthoastrocytomas, and pilocytic astrocytomas. NEURO-ONCOLOGY, PT II. 105:551-567.

PMID: 22230518

2012

Neurological complications of chemotherapy to the central nervous system. NEURO-ONCOLOGY, PT II. 105:903-916.

PMID: 22230541

2011

Successful Gamma Knife-based stereotactic radiosurgery treatment for medically intractable heterotopia-based seizure disorder. CLINICAL NEUROLOGY AND NEUROSURGERY. 113:934-936.

Full Text via DOI: 10.1016/j.clineuro.2011.06.012 PMID: 21803485

2011

Phase IB Study of Gene-Mediated Cytotoxic Immunotherapy Adjuvant to Up-Front Surgery and Intensive Timing Radiation for Malignant Glioma. JOURNAL OF CLINICAL ONCOLOGY. 29:3611-3619.

Full Text via DOI: 10.1200/JCO.2011.35.5222 PMID: 21844505

2011

Central Nervous System Cancers. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK. 352-400.

PMID: 21464144

2010

Clinical presentation, histology, and treatment in 430 patients with primary tumors of the spinal cord, spinal meninges, or cauda equina Clinical article. JOURNAL OF NEUROSURGERY-SPINE. 13:67-77.

Full Text via DOI: 10.3171/2010.3.SPINE09430 PMID: 20594020

2010

MicroRNAs and glioblastoma; the stem cell connection. CELL DEATH AND DIFFERENTIATION. 221-228.

Full Text via DOI: 10.1038/cdd.2009.71 PMID: 19521422

2010

Emergent Pulmonary Embolectomy and Advanced Glioblastoma Multiforme. CASE REPORTS IN MEDICINE. 2010.

Full Text via DOI: 10.1155/2010/862028 PMID: 21209739

2008

Primary meningeal CNS lymphoma treated with intra-arterial chemotherapy and blood-brain barrier disruption. JOURNAL OF NEURO-ONCOLOGY. 90:329-333.

Full Text via DOI: 10.1007/s11060-008-9667-5 PMID: 18758913

2008

Targeting of the Bmi-1 Oncogene/Stem Cell Renewal Factor by MicroRNA-128 Inhibits Glioma Proliferation and Self-Renewal. CANCER RESEARCH. 68:9125-9130.

Full Text via DOI: 10.1158/0008-5472.CAN-08-2629 PMID: 19010882

2008

A phase II study of thalidomide and irinotecan for treatment of glioblastoma multiforme. JOURNAL OF NEURO-ONCOLOGY. 90:229-235.

Full Text via DOI: 10.1007/s11060-008-9655-9 PMID: 18661102

2008

CNS germinomas: what is the best treatment strategy?. Expert review of neurotherapeutics. 1527-36.

Full Text via DOI: 10.1586/14737175.8.10.1527 PMID: 18928345

2008

Lithium inhibits invasion of glioma cells; possible involvement of glycogen synthase kinase-3. NEURO-ONCOLOGY. 10:690-699.

Full Text via DOI: 10.1215/15228517-2008-041 PMID: 18715951

2008

Aggressive papillary glioneuronal tumor: case report and literature review. CLINICAL NEUROPATHOLOGY. 27:317-324.

PMID: 18808063

2008

Glioblastoma multiforme. CURRENT TREATMENT OPTIONS IN NEUROLOGY. 285-294.

PMID: 18579015

2008

Do pilocytic astrocytomas have a benign course in adult patients?. NATURE CLINICAL PRACTICE NEUROLOGY. 296-297.

Full Text via DOI: 10.1038/ncpneuro0787 PMID: 18414467

2008

Central nervous system cancers.. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK. 456-504.

PMID: 18492461

2008

Neurological decompression illness and hematocrit: Analysis of a consecutive series of 200 recreational scuba divers. UNDERSEA & HYPERBARIC MEDICINE. 35:99-106.

PMID: 18500074

2008

Prognosis of refractory neurosarcoidosis altered by thalidomide: a case report.. Journal of medical case reports. 27.

Full Text via DOI: 10.1186/1752-1947-2-27 PMID: 18226232

2007

Small-molecule and antibody approaches to molecular chemotherapy of primary brain tumors. CURRENT OPINION IN INVESTIGATIONAL DRUGS. 1009-1021.

PMID: 18058572

2007

Neurological manifestations of decompression illness in recreational divers - the Cozumel experience.. UNDERSEA & HYPERBARIC MEDICINE. 34:349-357.

PMID: 18019086

2007

Retrospective analysis of the efficacy and tolerability of levetiracetam in patients with metastatic brain tumors. JOURNAL OF NEURO-ONCOLOGY. 84:293-296.

Full Text via DOI: 10.1007/s11060-007-9373-8 PMID: 17431542

2007

Hydroxyurea chemotherapy in the treatment of meningiomas.. NEUROSURGICAL FOCUS. E11.

PMID: 17961035

2007

Palliative care for patients with brain metastases. 215-233.

PMID: 18078273

2007

Symptom management and supportive care of the patient with brain metastases. 53-73.

PMID: 18078265

2006

Advances in strategies to improve drug delivery to brain tumors.. Expert review of neurotherapeutics. 1495-509.

PMID: 17078789

2006

Incidence of infusion plan alterations after angiography in patients undergoing intra-arterial chemotherapy for brain tumors. JOURNAL OF NEURO-ONCOLOGY. 78:157-160.

Full Text via DOI: 10.1007/s11060-005-9080-2 PMID: 16614945

2006

Retrospective analysis of the efficacy and tolerability of levetiracetam in brain tumor patients. JOURNAL OF NEURO-ONCOLOGY. 78:99-102.

Full Text via DOI: 10.1007/s11060-005-9070-4 PMID: 16541329

2006

Brain tumor imaging and cancer management: the neuro-oncologists perspective.. Topics in magnetic resonance imaging : TMRI. 127-36.

PMID: 17198229

2006

Cytotoxic and molecular chemotherapy for high-grade glioma: an emerging strategy for the future. EXPERT OPINION ON PHARMACOTHERAPY. 749-765.

Full Text via DOI: 10.1517/14656566.7.6.749 PMID: 16556090

2006

Prevalence and rupture rate of cerebral aneurysms discovered during intra-arterial chemotherapy of brain tumors. AMERICAN JOURNAL OF NEURORADIOLOGY. 27:297-299.

PMID: 16484396

2005

Intra-arterial chemotherapy of primary brain tumors.. CURRENT TREATMENT OPTIONS IN ONCOLOGY. 519-30.

PMID: 16242056

2005

Phase I trial of irinotecan plus temozolomide in adults with recurrent malignant glioma. CANCER. 104:1478-1486.

Full Text via DOI: 10.1002/cncr.21316 PMID: 16088964

2005

Central nervous system cancers: Clinical Practice Guidelines in Oncology.. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK. 644-90.

PMID: 16194456

2005

Molecular neuro-oncology and the development of targeted therapeutic strategies for brain tumors Part 5: Apoptosis and cell cycle. EXPERT REVIEW OF ANTICANCER THERAPY. 355-378.

Full Text via DOI: 10.1586/14737140.5.2.355 PMID: 15877531

2005

Molecular neuro-oncology and the development of targeted therapeutic strategies for brain tumors - Part 4: p53 signaling pathway. EXPERT REVIEW OF ANTICANCER THERAPY. 177-191.

Full Text via DOI: 10.1586/14737140.5.1.177 PMID: 15757449

2004

Hydroxyurea chemotherapy for meningiomas: enlarged cohort with extended follow-up. BRITISH JOURNAL OF NEUROSURGERY. 18:495-499.

Full Text via DOI: 10.1080/02688690400012392 PMID: 15799152

2004

Molecular neuro-oncology and the development of targeted therapeutic strategies for brain tumors. Part 3: brain tumor invasiveness.. Expert review of anticancer therapy. 803-21.

PMID: 15485315

2004

Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 2: PI3K/Akt/PTEN, mTOR, SHH/PTCH and angiogenesis.. EXPERT REVIEW OF ANTICANCER THERAPY. 105-28.

PMID: 14748662

2003

Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 1: Growth factor and Ras signaling pathways.. EXPERT REVIEW OF ANTICANCER THERAPY. 595-614.

PMID: 14599084

2003

Phase III study comparing three cycles of infusional carmustine and cisplatin followed by radiation therapy with radiation therapy and concurrent carmustine in patients with newly diagnosed supratentorial glioblastoma multiforme: Eastern Cooperative Oncology Group Trial 2394. JOURNAL OF CLINICAL ONCOLOGY. 21:1485-1491.

Full Text via DOI: 10.1200/JCO.2003.10.035 PMID: 12697871

2003

Intra-arterial carboplatin and intravenous etoposide for the treatment of metastatic brain tumors. JOURNAL OF NEURO-ONCOLOGY. 61:35-44.

PMID: 12587794

2002

Chemotherapy for the treatment of metastatic brain tumors.. EXPERT REVIEW OF ANTICANCER THERAPY. 495-506.

PMID: 12382518

2002

Visualization of microvascularity in glioblastoma multiforme with 8-T high-spatial-resolution MR imaging. AMERICAN JOURNAL OF NEURORADIOLOGY. 23:1553-1556.

PMID: 12372746

2002

Intra-arterial carboplatin and intravenous etoposide for the treatment of recurrent and progressive non-GBM gliomas. JOURNAL OF NEURO-ONCOLOGY. 56:79-86.

PMID: 11949830

2001

Brain metastases from fallopian tube carcinoma responsive to intra-arterial carboplatin and intravenous etoposide: a case report. JOURNAL OF NEURO-ONCOLOGY. 55:179-184.

PMID: 11859973

2001

Review of the molecular genetics and chemotherapeutic treatment of adult and paediatric medulloblastoma. EXPERT OPINION ON INVESTIGATIONAL DRUGS. 2089-2104.

PMID: 11772307

2001

Neurologic complications of scuba diving. AMERICAN FAMILY PHYSICIAN. 63:2211-2218.

PMID: 11417773

2000

Hydroxyurea chemotherapy for unresectable or residual meningioma. JOURNAL OF NEURO-ONCOLOGY. 49:165-170.

PMID: 11206012

1999

Brain tumors: Complications of cerebral angiography accompanied by intraarterial chemotherapy. RADIOLOGY. 213:135-140.

PMID: 10540653

1999

Clinical presentation, diagnosis, and pharmacotherapy of patients with primary brain tumors. ANNALS OF PHARMACOTHERAPY. 816-832.

PMID: 10466912

1999

Neurologic complications of systemic cancer. AMERICAN FAMILY PHYSICIAN. 59:878-886.

PMID: 10068711

1998

Interpretive risks: the use of the Hopkins Symptom Checklist 90 Revised (SCL 90-R) with brain tumour patients. BRAIN INJURY. 12:199-205.

PMID: 9547950

1997

Ethical issues in neuro-oncology. SEMINARS IN NEUROLOGY. 17:219-226.

PMID: 9311063

1996

Lhermitte's sign as a presenting symptom of primary spinal cord tumor. JOURNAL OF NEURO-ONCOLOGY. 29:183-188.

PMID: 8858524

1996

Extracranial plasma cell granuloma presenting as a diffuse meningeal and intraparenchymal mass. JOURNAL OF NEUROIMAGING. 6:58-60.

PMID: 8555666

1995

Spinal cord tumors: review of etiology, diagnosis, and multidisciplinary approach to treatment.. Cancer practice. 207-18.

PMID: 7620485

1995

Progressive multifocal leukoencephalopathy presenting as multiple enhancing lesions on MRI: case report and literature review.. JOURNAL OF NEUROIMAGING. 125-8.

PMID: 7718940

1995

COMMON NEUROLOGIC COMPLICATIONS OF HIV-1 INFECTION AND AIDS. AMERICAN FAMILY PHYSICIAN. 51:387-398.

PMID: 7840035

1995

ATTEMPTED DOSE INTENSIFIED CYCLOPHOSPHAMIDE, ETOPOSIDE, AND GRANULOCYTE-COLONY-STIMULATING FACTOR FOR TREATMENT OF MALIGNANT ASTROCYTOMA. JOURNAL OF NEURO-ONCOLOGY. 24:285-292.

PMID: 7595759

1994

SWALLOWING ASSESSMENT IN PRIMARY BRAIN-TUMOR PATIENTS WITH DYSPHAGIA. NEUROLOGY. 44:1927-1932.

PMID: 7936249

1994

HERPES-ZOSTER AND PROCARBAZINE THERAPY IN PATIENTS WITH MALIGNANT GLIOMA. INTERNATIONAL JOURNAL OF ONCOLOGY. 5:97-100.

PMID: 21559563

1994

PRIMARY BRAIN-TUMORS - REVIEW OF ETIOLOGY, DIAGNOSIS AND TREATMENT. AMERICAN FAMILY PHYSICIAN. 49:787-797.

PMID: 8116514

1993

COMPARISON BETWEEN BCNU AND PROCARBAZINE CHEMOTHERAPY FOR TREATMENT OF GLIOMAS. JOURNAL OF NEURO-ONCOLOGY. 15:257-263.

PMID: 8360711

1992

EXTRANEURAL METASTASES IN EPENDYMOMA. JOURNAL OF NEURO-ONCOLOGY. 14:135-142.

PMID: 1432036

1992

EXTRANEURAL METASTASES OF INFRATENTORIAL GLIOBLASTOMA-MULTIFORME TO THE PERITONEAL-CAVITY. CANCER. 69:2149-2153.

PMID: 1311985

1991

ONE-AND-A-HALF SYNDROME AFTER A RESECTION OF A MIDLINE CEREBELLAR ASTROCYTOMA - CASE-REPORT AND DISCUSSION OF THE LITERATURE. NEUROSURGERY. 29:768-772.

PMID: 1961411

1991

TURCOTS-SYNDROME - FLOW CYTOMETRIC ANALYSIS. CANCER. 68:1633-1639.

PMID: 1654200

1991

GLUCOSEPHOSPHATE ISOMERASE AS A CSF MARKER FOR LEPTOMENINGEAL METASTASIS. NEUROLOGY. 41:395-398.

PMID: 2006007

1990

PROCARBAZINE CHEMOTHERAPY IN THE TREATMENT OF RECURRENT MALIGNANT ASTROCYTOMAS AFTER RADIATION AND NITROSOUREA FAILURE. NEUROLOGY. 40:1743-1746.

PMID: 2172864

1989

INTRA-ARTERIAL CISPLATIN FOR THE TREATMENT OF MALIGNANT GLIOMAS. JOURNAL OF NEURO-ONCOLOGY. 7:39-45.

PMID: 2547032

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