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Cornnell, Heather, PhD
Overview
overview
- Dr. Heather Cornnell is the Senior Research Scientist who heads the Research Imaging Core at the TRI. She has advanced degrees in Chemistry, Chemical Engineering and Biomedical Engineering, with a specialization in Image Processing and Analyses from the University of Florida. She started at the TRI in 2011 after completing a postdoctoral fellowship at the Moffitt Cancer Research Institute in imaging animal models of cancer. As one of the original members of the TRI team, she has developed and optimized the MRI, DEXA and Fibroscan acquisition and quality procedures for the core, including multinuclear spectroscopy, MR image se
Affiliation
Member of
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Clinical Program
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Research Department
Publications
Most Recent Publications
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2023Comprehensive interrogation of human skeletal muscle reveals a dissociation between insulin resistance and mitochondrial capacity. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 325:E291-E302.Full Text via DOI: 10.1152/ajpendo.00143.2023 PMID: 37584609
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2023The proteome and phosphoproteome of circulating extracellular vesicle-enriched preparations are associated with characteristic clinical features in type 1 diabetes. FRONTIERS IN ENDOCRINOLOGY. 14.Full Text via DOI: 10.3389/fendo.2023.1219293 PMID: 37576973
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2021Weight Loss and Exercise Differentially Affect Insulin Sensitivity, Body Composition, Cardiorespiratory Fitness, and Muscle Strength in Older Adults With Obesity: A Randomized Controlled Trial. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES.Full Text via DOI: 10.1093/gerona/glab240 PMID: 34406407
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2020Development of a Device-to-Image Registration Free Needle Guide for Magnetic Resonance Imaging-Guided Targeted Prostate Biopsy. JOURNAL OF MEDICAL DEVICES-TRANSACTIONS OF THE ASME. 14.Full Text via DOI: 10.1115/1.4047874
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2020Older adults with sarcopenia have distinct skeletal muscle phosphodiester, phosphocreatine, and phospholipid profiles. AGING CELL. 19.Full Text via DOI: 10.1111/acel.13135 PMID: 32468656
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2019Endurance training remodels skeletal muscle phospholipid composition and increases intrinsic mitochondrial respiration in men with Type 2 diabetes. PHYSIOLOGICAL GENOMICS. 51:586-595.Full Text via DOI: 10.1152/physiolgenomics.00014.2019 PMID: 31588872
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2019MRI-GUIDED, TRANSPERINEAL PROSTATE BIOPSY USING FIXED COORDINATE NEEDLE GUIDE: INITIAL FEASIBILITY STUDY. 2019 DESIGN OF MEDICAL DEVICES CONFERENCE.Full Text via DOI: 10.1115/DMD2019-3281
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2018Exercise Response Variations in Skeletal Muscle PCr Recovery Rate and Insulin Sensitivity Relate to Muscle Epigenomic Profiles in Individuals With Type 2 Diabetes. DIABETES CARE. 41:2245-2254.Full Text via DOI: 10.2337/dc18-0296 PMID: 30072402
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2018Physical activity unveils the relationship between mitochondrial energetics, muscle quality, and physical function in older adults. JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE. 9:279-294.Full Text via DOI: 10.1002/jcsm.12272 PMID: 29368427
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2018Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance. MOLECULAR METABOLISM. 7:1-11.Full Text via DOI: 10.1016/j.molmet.2017.10.012 PMID: 29146412
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2017Effects of 12 Months of Caloric Restriction on Muscle Mitochondrial Function in Healthy Individuals. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 102:111-121.Full Text via DOI: 10.1210/jc.2016-3211 PMID: 27778643
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2016Differences in Mitochondrial Coupling Reveal a Novel Signature of Mitohormesis in Muscle of Healthy Individuals. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 101:4994-5003.Full Text via DOI: 10.1210/jc.2016-2742 PMID: 27710240
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2016MR Imaging Biomarkers to Monitor Early Response to Hypoxia-Activated Prodrug TH-302 in Pancreatic Cancer Xenografts. PLOS ONE. 11.Full Text via DOI: 10.1371/journal.pone.0155289 PMID: 27227903
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2014Evaluation of the "Steal" Phenomenon on the Efficacy of Hypoxia Activated Prodrug TH-302 in Pancreatic Cancer. PLOS ONE. 9.Full Text via DOI: 10.1371/journal.pone.0113586 PMID: 25532146
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2014Mechanisms of buffer therapy resistance. NEOPLASIA. 16:354-+.Full Text via DOI: 10.1016/j.neo.2014.04.005 PMID: 24862761
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2014Safety and Chemopreventive Effect of Polyphenon E in Preventing Early and Metastatic Progression of Prostate Cancer in TRAMP Mice. CANCER PREVENTION RESEARCH. 7:435-444.Full Text via DOI: 10.1158/1940-6207.CAPR-13-0427-T PMID: 24501325
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2013Development and in Vivo Quantitative Magnetic Resonance Imaging of Polymer Micelles Targeted to the Melanocortin 1 Receptor. JOURNAL OF MEDICINAL CHEMISTRY. 56:6330-6338.Full Text via DOI: 10.1021/jm4005576 PMID: 23863078
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2013Acidity Generated by the Tumor Microenvironment Drives Local Invasion. CANCER RESEARCH. 73:1524-1535.Full Text via DOI: 10.1158/0008-5472.CAN-12-2796 PMID: 23288510
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2012Systemic Buffers Inhibit Carcinogenesis in TRAMP Mice. JOURNAL OF UROLOGY. 188:624-631.Full Text via DOI: 10.1016/j.juro.2012.03.113 PMID: 22704445
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2011Reduction of metastasis using a non-volatile buffer. CLINICAL & EXPERIMENTAL METASTASIS. 28:841-849.Full Text via DOI: 10.1007/s10585-011-9415-7 PMID: 21861189
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2011Free Base Lysine Increases Survival and Reduces Metastasis in Prostate Cancer Model.. Journal of cancer science & therapy.PMID: 24032073
Background
Full Name
- Heather Cornnell, PhD
Education
- University of Florida, Gainesville, FL
Contact
primary email
- Research.Institute@AdventHealth.com