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Pigula, Frank, MD
Overview
overview
- Frank Pigula, MD, is an internationally recognized expert in complex congenital heart disease. He previously served as clinical director of the pediatric cardiac surgery program at the Children’s Hospital of Boston and is a former associate professor of surgery at Harvard University Medical School. Extensively published in peer-reviewed medical journals, Dr. Pigula conducts ongoing clinical studies to document neurodevelopmental outcomes in infants using a technique he developed to reduce circulatory arrest times in an effort to reduce bypass-related neurologic injury. Dr. Pigula has extensive experience in neonatal cardiac surgery.
research areas
Affiliation
Member of
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Clinical Program
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Research Department
Publications
Most Recent Publications
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2021Successful Surgical Management of Aortic Arch Thrombosis in the Neonate. ANNALS OF THORACIC SURGERY. 111:E105-E108.Full Text via DOI: 10.1016/j.athoracsur.2020.05.091 PMID: 32673659
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2019Changes in tissue oxygen tension, venous saturation, and Fick-based assessments of cardiac output during hyperoxia. ACTA ANAESTHESIOLOGICA SCANDINAVICA. 63:93-100.Full Text via DOI: 10.1111/aas.13225 PMID: 30109703
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2019Rates of Interventions in Isolated Coarctation Repair in Neonates Versus Infants: Does Age Matter ?. ANNALS OF THORACIC SURGERY. 107:180-186.Full Text via DOI: 10.1016/j.athoracsur.2018.07.016 PMID: 30179626
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2018Towards Alternative Approaches for Coupling of a Soft Robotic Sleeve to the Heart. ANNALS OF BIOMEDICAL ENGINEERING. 46:1534-1547.Full Text via DOI: 10.1007/s10439-018-2046-2 PMID: 29766347
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2017Pseudoaneurysm complicating right ventricle-to-pulmonary artery conduit surgery: Incidence and risk factors. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 154:2046-2049.Full Text via DOI: 10.1016/j.jtcvs.2017.08.014 PMID: 28919137
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2017An Implantable Extracardiac Soft Robotic Device for the Failing Heart: Mechanical Coupling and Synchronization. SOFT ROBOTICS. 4:241-250.Full Text via DOI: 10.1089/soro.2016.0076 PMID: 29182083
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2017Management of Tricuspid Regurgitation in Patients With Hypoplastic Left Heart Syndrome. SEMINARS IN THORACIC AND CARDIOVASCULAR SURGERY. 29:64-69.Full Text via DOI: 10.1053/j.semtcvs.2017.02.004 PMID: 28684000
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2017Soft robotic sleeve supports heart function. SCIENCE TRANSLATIONAL MEDICINE. 9.Full Text via DOI: 10.1126/scitranslmed.aaf3925 PMID: 28100834
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2017The use of soft robotics in cardiovascular therapy. EXPERT REVIEW OF CARDIOVASCULAR THERAPY. 767-774.Full Text via DOI: 10.1080/14779072.2017.1366313 PMID: 28817983
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2016Anomalous Aortic Origin of Coronary Arteries: A Single-Center Experience. SEMINARS IN THORACIC AND CARDIOVASCULAR SURGERY. 28:791-800.Full Text via DOI: 10.1053/j.semtcvs.2016.08.012 PMID: 28417866
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2016Outcome and performance of bioprosthetic pulmonary valve replacement in patients with congenital heart disease. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 152:1333-1340.Full Text via DOI: 10.1016/j.jtcvs.2016.06.064 PMID: 27637422
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2016Phosphodiesterase Inhibitor-Based Vasodilation Improves Oxygen Delivery and Clinical Outcomes Following Stage 1 Palliation. JOURNAL OF THE AMERICAN HEART ASSOCIATION. 5.Full Text via DOI: 10.1161/JAHA.116.003554 PMID: 27806964
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2016Technical Performance Score Predicts Resource Utilization in Congenital Cardiac Procedures. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2696-2698.Full Text via DOI: 10.1016/j.jacc.2016.03.545 PMID: 27256837
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2016Arterial Limb Microemboli during Cardiopulmonary Bypass: Observations from a Congenital Cardiac Surgery Practice.. The journal of extra-corporeal technology. 5-10.PMID: 27134302
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2016Biventricular repair for common atrioventricular canal defect with parachute left atrioventricular valve. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY. 49:546-552.Full Text via DOI: 10.1093/ejcts/ezv114 PMID: 25838456
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2016Are Bioprosthetic Valves Appropriate for Aortic Valve Replacement in Young Patients?. Seminars in thoracic and cardiovascular surgery. Pediatric cardiac surgery annual. 63-7.Full Text via DOI: 10.1053/j.pcsu.2015.12.005 PMID: 27060046
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2016Fractures Related to Metabolic Bone Disease in Children with Congenital Heart Disease. CONGENITAL HEART DISEASE. 11:80-86.Full Text via DOI: 10.1111/chd.12293 PMID: 26302998
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2015The Safety and Efficacy of Antifibrinolytic Therapy in Neonatal Cardiac Surgery. PLOS ONE. 10.Full Text via DOI: 10.1371/journal.pone.0126514 PMID: 25954976
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2015Aortic root translocation (Nikaidoh procedure): Intermediate follow-up and impact of conduit type. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 149:1349-1355.Full Text via DOI: 10.1016/j.jtcvs.2014.11.014 PMID: 25500103
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2015The Taussig-Bing anomaly turns 65: What we have learned in a lifetime. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 1132-1133.Full Text via DOI: 10.1016/j.jtcvs.2014.11.010 PMID: 25483896
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2015Evaluation of Cerebral Oxygenation and Perfusion With Conversion From an Arterial-to-Systemic Shunt Circulation to the Bidirectional Glenn Circulation in Patients With Univentricular Cardiac Abnormalities. JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA. 29:95-100.Full Text via DOI: 10.1053/j.jvca.2014.06.001 PMID: 25440622
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2015Neonatal Mitral Valve Repair in Biventricular Repair, Single Ventricle Palliation, and Secondary Left Ventricular Recruitment: Indications, Techniques, and Mid-Term Outcomes. FRONTIERS IN SURGERY. 2.Full Text via DOI: 10.3389/fsurg.2015.00059 PMID: 26618162
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2015Ring-Reinforced Sano Conduit at Norwood Stage I Reduces Proximal Conduit Obstruction. ANNALS OF THORACIC SURGERY. 99:171-179.Full Text via DOI: 10.1016/j.athoracsur.2014.08.078 PMID: 25441064
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2014Outcomes differ in patients who undergo immediate intraoperative revision versus patients with delayed postoperative revision of residual lesions in congenital heart operations. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 148:2540-2546.Full Text via DOI: 10.1016/j.jtcvs.2014.07.073 PMID: 25173124
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2014Technical Performance Scoreas Predictor for Post-discharge Reintervention in Valve-Sparing Tetralogy of Fallot Repair. SEMINARS IN THORACIC AND CARDIOVASCULAR SURGERY. 26:297-303.Full Text via DOI: 10.1053/j.semtcvs.2014.12.001 PMID: 25837542
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2014Isolated pulmonary artery arising from a duct: A single-center review of diagnostic and therapeutic strategies. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 148:2245-2252.Full Text via DOI: 10.1016/j.jtcvs.2013.11.047 PMID: 24521948
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2014Leaving the nest: Facing adulthood after the arterial switch operation. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 2199-2200.Full Text via DOI: 10.1016/j.jtcvs.2014.09.096 PMID: 25444192
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2014Aspirin unresponsiveness predicts thrombosis in high-risk pediatric patients after cardiac surgery. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 148:810-814.Full Text via DOI: 10.1016/j.jtcvs.2014.06.016 PMID: 25129584
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2014Association between Technical Performance Scores and neurodevelopmental outcomes after congenital cardiac surgery. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 148:232-U828.Full Text via DOI: 10.1016/j.jtcvs.2013.08.032 PMID: 24084277
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2014Risk factors for prolonged length of stay after the stage 2 procedure in the single-ventricle reconstruction trial. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 147:1791-U134.Full Text via DOI: 10.1016/j.jtcvs.2013.07.063 PMID: 24075564
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2014A Bioinspired Soft Actuated Material. ADVANCED MATERIALS. 26:1200-1206.Full Text via DOI: 10.1002/adma.201304018 PMID: 24227698
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2014Hypercoagulability panel testing predicts thrombosis in neonates undergoing cardiac surgery. AMERICAN JOURNAL OF HEMATOLOGY. 89:151-155.Full Text via DOI: 10.1002/ajh.23607 PMID: 24123221
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2014Surgical approaches to critical aortic stenosis with unicommissural valve in neonates. EXPERT REVIEW OF CARDIOVASCULAR THERAPY. 12:1401-1405.Full Text via DOI: 10.1586/14779072.2014.977257 PMID: 25366940
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2014Technical Performance Scores are strongly associated with early mortality, postoperative adverse events, and intensive care unit length of stay-analysis of consecutive discharges for 2 years. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 147:389-+.Full Text via DOI: 10.1016/j.jtcvs.2013.07.044 PMID: 24035318
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2013The radiographic appearance of split Blake drains: what you see is not necessarily what you get. PEDIATRIC RADIOLOGY. 43:1573-1576.Full Text via DOI: 10.1007/s00247-013-2749-3 PMID: 23843132
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2013Surgical repair of truncal valve regurgitation. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY. 44:813-820.Full Text via DOI: 10.1093/ejcts/ezt213 PMID: 23625452
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2013An Extracorporeal Membrane Oxygenation Cannulation Curriculum Featuring a Novel Integrated Skills Trainer Leads to Improved Performance Among Pediatric Cardiac Surgery Trainees. SIMULATION IN HEALTHCARE-JOURNAL OF THE SOCIETY FOR SIMULATION IN HEALTHCARE. 8:221-228.Full Text via DOI: 10.1097/SIH.0b013e31828b4179 PMID: 23588057
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2013Hypercoagulability Markers Predict Thrombosis in Single Ventricle Neonates Undergoing Cardiac Surgery. ANNALS OF THORACIC SURGERY. 96:651-656.Full Text via DOI: 10.1016/j.athoracsur.2013.04.061 PMID: 23809731
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2013Inadequate Technical Performance Scores Are Associated With Late Mortality and Late Reintervention. ANNALS OF THORACIC SURGERY. 96:664-669.Full Text via DOI: 10.1016/j.athoracsur.2013.04.043 PMID: 23782646
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2013Predictors of Reintervention After Repair of Interrupted Aortic Arch With Ventricular Septal Defect. ANNALS OF THORACIC SURGERY. 96:621-628.Full Text via DOI: 10.1016/j.athoracsur.2013.04.027 PMID: 23816413
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2013Biventricular Conversion After Single-Ventricle Palliation in Unbalanced Atrioventricular Canal Defects. ANNALS OF THORACIC SURGERY. 95:2086-2096.Full Text via DOI: 10.1016/j.athoracsur.2013.01.075 PMID: 23602070
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2013Left Ventricle After Palliation of Hypoplastic Left Heart Syndrome: Friend, Fiend, or Innocent Bystander?. PEDIATRIC CARDIOLOGY. 1063-1072.Full Text via DOI: 10.1007/s00246-013-0677-5 PMID: 23519686
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2013A single-center experience with luminal venous cannulae obstruction caused by clot formation during bypass.. The journal of extra-corporeal technology. 55-7.PMID: 23691786
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2013Unplanned reinterventions are associated with postoperative mortality in neonates with critical congenital heart disease. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 145:671-677.Full Text via DOI: 10.1016/j.jtcvs.2012.03.078 PMID: 22578897
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2013Design and Rationale of Safe Pediatric Euglycemia After Cardiac Surgery: A Randomized Controlled Trial of Tight Glycemic Control After Pediatric Cardiac Surgery. PEDIATRIC CRITICAL CARE MEDICINE. 14:148-156.Full Text via DOI: 10.1097/PCC.0b013e31825b549a PMID: 22805161
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2013Outcomes of transcatheter approach for initial treatment of pulmonary atresia with intact ventricular septum. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS. 81:111-118.Full Text via DOI: 10.1002/ccd.24288 PMID: 23076881
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2012Staged Left Ventricular Recruitment After Single-Ventricle Palliation in Patients With Borderline Left Heart Hypoplasia. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 60:1966-1974.Full Text via DOI: 10.1016/j.jacc.2012.07.041 PMID: 23062531
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2012Congenital heart surgeon's technical proficiency affects neonatal hospital survival. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 144:1119-1124.Full Text via DOI: 10.1016/j.jtcvs.2012.02.007 PMID: 22421402
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2012Surgical technical performance scores are predictors of late mortality and unplanned reinterventions in infants after cardiac surgery. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 144:1095-+.Full Text via DOI: 10.1016/j.jtcvs.2012.07.081 PMID: 22939862
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2012Protecting the Infant Brain During Cardiac Surgery: A Systematic Review. ANNALS OF THORACIC SURGERY. 1365-1373.Full Text via DOI: 10.1016/j.athoracsur.2012.05.135 PMID: 23006704
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2012Technical Performance Scores in Congenital Cardiac Operations: A Quality Assessment Initiative. ANNALS OF THORACIC SURGERY. 94:1317-1323.Full Text via DOI: 10.1016/j.athoracsur.2012.05.014 PMID: 22795058
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2012Tight Glycemic Control versus Standard Care after Pediatric Cardiac Surgery. NEW ENGLAND JOURNAL OF MEDICINE. 367:1208-1219.Full Text via DOI: 10.1056/NEJMoa1206044 PMID: 22957521
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2012Inhaled Carbon Monoxide Provides Cerebral Cytoprotection in Pigs. PLOS ONE. 7.Full Text via DOI: 10.1371/journal.pone.0041982 PMID: 22879904
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2012Biventricular strategies for neonatal critical aortic stenosis: High mortality associated with early reintervention. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 144:409-+.Full Text via DOI: 10.1016/j.jtcvs.2011.09.076 PMID: 22326425
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2012Improving Left Ventricular Outflow Tract Obstruction Repair in Common Atrioventricular Canal Defects. ANNALS OF THORACIC SURGERY. 94:599-605.Full Text via DOI: 10.1016/j.athoracsur.2012.04.009 PMID: 22626757
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2012Outcome after repair of atrioventricular septal defect with tetralogy of Fallot. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 143:338-343.Full Text via DOI: 10.1016/j.jtcvs.2011.05.031 PMID: 21855095
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2012Younger age and valve oversizing are predictors of structural valve deterioration after pulmonary valve replacement in patients with tetralogy of Fallot. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 143:352-360.Full Text via DOI: 10.1016/j.jtcvs.2011.10.079 PMID: 22153723
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2012Ebstein's Malformation of the Tricuspid Valve: Short-term Outcomes of the "Cone Procedure" versus Conventional Surgery. CONGENITAL HEART DISEASE. 7:50-58.Full Text via DOI: 10.1111/j.1747-0803.2011.00603.x PMID: 22176641
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2011Outcomes and Risk Factors for Mortality in Premature Neonates With Critical Congenital Heart Disease. PEDIATRIC CARDIOLOGY. 32:1139-1146.Full Text via DOI: 10.1007/s00246-011-0036-3 PMID: 21713439
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2011Intraoperative adverse events can be compensated by technical performance in neonates and infants after cardiac surgery: A prospective study. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 142:1098-U576.Full Text via DOI: 10.1016/j.jtcvs.2011.07.003 PMID: 21840545
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2011Early Postoperative Severity of Illness Predicts Outcomes After the Stage I Norwood Procedure. ANNALS OF THORACIC SURGERY. 92:660-665.Full Text via DOI: 10.1016/j.athoracsur.2011.03.086 PMID: 21704285
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2011Anomalous left coronary artery arising from the pulmonary artery in hypoplastic left hearts: Case series and review of literature. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 225-227.Full Text via DOI: 10.1016/j.jtcvs.2010.10.031 PMID: 21247594
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2011Early Reintervention on the Pulmonary Arteries and Right Ventricular Outflow Tract After Neonatal or Early Infant Repair of Truncus Arteriosus Using Homograft Conduits. AMERICAN JOURNAL OF CARDIOLOGY. 108:106-113.Full Text via DOI: 10.1016/j.amjcard.2011.03.006 PMID: 21530938
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2011Massive air embolism in a Fontan patient.. The journal of extra-corporeal technology. 79-83.PMID: 21848177
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2011Survival of Children Requiring Repeat Extracorporeal Membrane Oxygenation After Congenital Heart Surgery. ANNALS OF THORACIC SURGERY. 91:1949-1955.Full Text via DOI: 10.1016/j.athoracsur.2011.01.078 PMID: 21514563
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2011Variation in Preoperative and Intraoperative Care for First-stage Palliation of Single-ventricle Heart Disease: A Report from the Joint Council on Congenital Heart Disease National Quality Improvement Collaborative. CONGENITAL HEART DISEASE. 6:108-115.Full Text via DOI: 10.1111/j.1747-0803.2011.00508.x PMID: 21426524
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2011Late Pulmonary Valve Replacement in Patients With Pulmonary Atresia and Intact Ventricular Septum: A Case-Matched Study. ANNALS OF THORACIC SURGERY. 91:555-560.Full Text via DOI: 10.1016/j.athoracsur.2010.09.024 PMID: 21256313
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2011Right Ventricle and Tricuspid Valve Function at Midterm After the Fontan Operation for Hypoplastic Left Heart Syndrome: Impact of Shunt Type. PEDIATRIC CARDIOLOGY. 32:160-166.Full Text via DOI: 10.1007/s00246-010-9835-1 PMID: 21107554
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2011Blood Transfusion After Pediatric Cardiac Surgery Is Associated With Prolonged Hospital Stay. ANNALS OF THORACIC SURGERY. 91:204-211.Full Text via DOI: 10.1016/j.athoracsur.2010.07.037 PMID: 21172513
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2010Relationship of Intraoperative Cerebral Oxygen Saturation to Neurodevelopmental Outcome and Brain Magnetic Resonance Imaging at 1 Year of Age in Infants Undergoing Biventricular Repair. CIRCULATION. 122:245-254.Full Text via DOI: 10.1161/CIRCULATIONAHA.109.902338 PMID: 20606124
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2010Intraoperative assessment after pediatric cardiac surgical repair: Initial experience with C-arm angiography. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. E1-E3.Full Text via DOI: 10.1016/j.jtcvs.2009.10.030 PMID: 20620370
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2010Report of the Pediatric Heart Network and National Heart, Lung, and Blood Institute Working Group on the Perioperative Management of Congenital Heart Disease. CIRCULATION. 121:2766-2772.Full Text via DOI: 10.1161/CIRCULATIONAHA.109.913129 PMID: 20585021
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2010Risk Factors for Surgical Site Infection After Cardiac Surgery in Children. ANNALS OF THORACIC SURGERY. 89:1833-1842.Full Text via DOI: 10.1016/j.athoracsur.2009.08.081 PMID: 20494036
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2010The Children's Hospital Boston non-routine event reporting program.. The journal of extra-corporeal technology. 158-62.PMID: 20648903
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2010Neonatal Closure of a Large Coronary-Cameral Fistula in a Case of Single Coronary Artery: The Utility of Intraoperative Angiography. JOURNAL OF CARDIAC SURGERY. 228-230.Full Text via DOI: 10.1111/j.1540-8191.2009.00957.x PMID: 20021512
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2010Aortic Translocation for the Management of Double-Outlet Right Ventricle and Pulmonary Stenosis With Dextrocardia: Technique to Avoid Coronary Insufficiency. ANNALS OF THORACIC SURGERY. 89:633-635.Full Text via DOI: 10.1016/j.athoracsur.2009.07.056 PMID: 20103367
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2009Primary left ventricular rehabilitation is effective in maintaining two-ventricle physiology in the borderline left heart. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 138:1276-1282.Full Text via DOI: 10.1016/j.jtcvs.2009.08.009 PMID: 19819471
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2009The needle and the damage done: pericardial effusion with tamponade after needle ingestion in an infant. JOURNAL OF LARYNGOLOGY AND OTOLOGY. 123:1396-1398.Full Text via DOI: 10.1017/S0022215109005672 PMID: 19545459
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2009Long-term results of right ventricular outflow tract reconstruction in neonatal cardiac surgery: Options and outcomes. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 138:911-916.Full Text via DOI: 10.1016/j.jtcvs.2008.10.058 PMID: 19660342
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2009Preoperative Extracorporeal Membrane Oxygenation as a Bridge to Cardiac Surgery in Children With Congenital Heart Disease. ANNALS OF THORACIC SURGERY. 88:1306-1311.Full Text via DOI: 10.1016/j.athoracsur.2009.06.074 PMID: 19766826
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2009Outcomes After Anatomic Repair for D-Transposition of the Great Arteries With Left Ventricular Outflow Tract Obstruction. CIRCULATION. 120:S53-S58.Full Text via DOI: 10.1161/CIRCULATIONAHA.108.843102 PMID: 19752386
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2009Hemostatic consequences of a non-fresh or reconstituted whole blood small volume cardiopulmonary bypass prime in neonates and infants. PEDIATRIC ANESTHESIA. 19:854-861.Full Text via DOI: 10.1111/j.1460-9592.2009.03110.x PMID: 19691693
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2009Right Ventricle to Pulmonary Artery Conduit Augmentation Compared With Replacement in Young Children. ANNALS OF THORACIC SURGERY. 88:574-580.Full Text via DOI: 10.1016/j.athoracsur.2009.04.103 PMID: 19632414
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2009Subtle hemorrhagic brain injury is associated with neurodevelopmental impairment in infants with repaired congenital heart disease. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 138:374-381.Full Text via DOI: 10.1016/j.jtcvs.2009.02.027 PMID: 19619781
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2009Removal of a sewing needle from an occult esophageal ingestion in a 9-month-old. JOURNAL OF PEDIATRIC SURGERY. 44:1450-1453.Full Text via DOI: 10.1016/j.jpedsurg.2009.02.055 PMID: 19573678
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2009Cerebral Oximetry During Infant Cardiac Surgery: Evaluation and Relationship to Early Postoperative Outcome. ANESTHESIA AND ANALGESIA. 108:1122-1131.Full Text via DOI: 10.1213/ane.0b013e318199dcd2 PMID: 19299774
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2009Truncus Arteriosus: Diagnostic Accuracy, Outcomes, and Impact of Prenatal Diagnosis. PEDIATRIC CARDIOLOGY. 30:256-261.Full Text via DOI: 10.1007/s00246-008-9328-7 PMID: 19015910
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2009Biventricular repair in patients with heterotaxy syndrome. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 137:371-379.Full Text via DOI: 10.1016/j.jtcvs.2008.10.027 PMID: 19185155
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2009Pulmonary Valve Replacement in Tetralogy of Fallot Impact on Survival and Ventricular Tachycardia. CIRCULATION. 119:445-451.Full Text via DOI: 10.1161/CIRCULATIONAHA.108.775221 PMID: 19139389
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2008True Aneurysmal Dilatation of a Contegra Conduit after Right Ventricular Outflow Tract Reconstruction: A Novel Mechanism of Conduit Failure. ANNALS OF THORACIC SURGERY. 1976-1977.Full Text via DOI: 10.1016/j.athoracsur.2008.04.104 PMID: 19022025
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2008Association Between Intraoperative and Early Postoperative Glucose Levels and Adverse Outcomes After Complex Congenital Heart Surgery. CIRCULATION. 118:2235-2242.Full Text via DOI: 10.1161/CIRCULATIONAHA.108.804286 PMID: 19001022
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2008Measurement of technical performance in surgery for congenital heart disease: The stage I Norwood procedure. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 136:993-U13.Full Text via DOI: 10.1016/j.jtcvs.2007.12.091 PMID: 18954641
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2008Mitral valve replacement in infants and children 5 years of age or younger: Evolution in practice and outcome over three decades with a focus on supra-annular prosthesis implantation. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 136:954-U8.Full Text via DOI: 10.1016/j.jtcvs.2007.12.076 PMID: 18954636
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2008Factors associated with prolonged recovery after the Fontan operation. CIRCULATION. 118:S171-S176.Full Text via DOI: 10.1161/CIRCULATIONAHA.107.750596 PMID: 18824751
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2008Ventricular function deteriorates with recurrent coarctation in hypoplastic left heart syndrome. ANNALS OF THORACIC SURGERY. 86:869-874.Full Text via DOI: 10.1016/j.athoracsur.2008.04.074 PMID: 18721575
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2008Survival and clinical course at Fontan after stage one palliation with either a modified Blalock-Taussig shunt or a right ventricle to pulmonary artery conduit. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 52:52-59.Full Text via DOI: 10.1016/j.jacc.2008.03.034 PMID: 18582635
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2008Jugular venous valved conduit (Contegra (R)) matches allograft performance in infant truncus arteriosus repair. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY. 33:890-898.Full Text via DOI: 10.1016/j.ejcts.2007.12.052 PMID: 18313324
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2008Randomized trial of hematocrit 25% versus 35% during hypothermic cardiopulmonary bypass in infant heart surgery. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 135:347-U97.Full Text via DOI: 10.1016/j.jtcvs.2007.01.051 PMID: 18242267
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2008Surgical outcome for patients with the mitral stenosis - aortic atresia variant of hypoplastic left heart syndrome. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 135:339-346.Full Text via DOI: 10.1016/j.jtcvs.2007.09.007 PMID: 18242265
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2008The effect of hematocrit during hypothermic cardiopulmonary bypass in infant heart surgery: Results from the combined Boston hematocrit trials. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 135:355-360.Full Text via DOI: 10.1016/j.jtcvs.2007.03.067 PMID: 18242268
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2007Critical left ventricular outflow tract obstruction: The disproportionate impact of biventricular repair in borderline cases. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 134:1429-1437.Full Text via DOI: 10.1016/j.jtcvs.2007.07.052 PMID: 18023658
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2007Contemporary Results and Current Strategies in the Management of Hypoplastic Left Heart Syndrome. SEMINARS IN THORACIC AND CARDIOVASCULAR SURGERY. 19:238-244.Full Text via DOI: 10.1053/j.semtcvs.2007.07.002 PMID: 17983951
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2007Hypoplastic left heart syndrome with intact or highly restrictive atrial septum: Surgical experience from a single center. ANNALS OF THORACIC SURGERY. 84:581-586.Full Text via DOI: 10.1016/j.athoracsur.2007.04.017 PMID: 17643639
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2007Liver transplantation in children with congenital heart disease. PEDIATRIC TRANSPLANTATION. 461-462.Full Text via DOI: 10.1111/j.1399-3046.2007.00734.x PMID: 17631011
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2007Mitral valve chordal rupture masquerades as endocarditis. PEDIATRIC CARDIOLOGY. 28:297-299.Full Text via DOI: 10.1007/s00246-006-0025-0 PMID: 17563828
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2007Coarctectomy reduces neoaortic arch obstruction in hypoplastic left heart syndrome. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 133:1540-1544.Full Text via DOI: 10.1016/j.jtcvs.2006.12.067 PMID: 17532953
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2007Early repair of hemitruncus: Excellent early and late outcomes. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 133:1329-1335.Full Text via DOI: 10.1016/j.jtcvs.2006.12.041 PMID: 17467452
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2007Surgery for aortic arch disease in the neonate. PEDIATRIC CARDIOLOGY. 28:134-143.Full Text via DOI: 10.1007/s00246-006-1451-8 PMID: 17265107
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2007Transcatheter creation and enlargement of ventricular septal defects for relief of ventricular hypertension. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 133:912-918.Full Text via DOI: 10.1016/j.jtcvs.2006.09.037 PMID: 17382625
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2007Anticoagulation and pediatric extracorporeal membrane oxygenation: Impact of activated clotting time and heparin dose on survival. ANNALS OF THORACIC SURGERY. 83:912-920.Full Text via DOI: 10.1016/j.athoracsur.2006.09.054 PMID: 17307433
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2007Measurement of technical performance in congenital heart surgery: A pilot study. ANNALS OF THORACIC SURGERY. 83:179-184.Full Text via DOI: 10.1016/j.athoracsur.2006.07.031 PMID: 17184656
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2006Aortic atresia or severe left ventricular outflow tract obstruction with ventricular septal defect: Results of primary biventricular repair in neonates. ANNALS OF THORACIC SURGERY. 82:2227-2232.Full Text via DOI: 10.1016/j.athoracsur.2006.05.124 PMID: 17126139
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2006Regional low-flow perfusion versus circulatory arrest in neonates: One-year neurodevelopmental outcome. ANNALS OF THORACIC SURGERY. 82:2207-2213.Full Text via DOI: 10.1016/j.athoracsur.2006.06.069 PMID: 17126136
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2006Real-time continuous glucose monitoring in pediatric patients during and after cardiac surgery. PEDIATRICS. 1176-1184.Full Text via DOI: 10.1542/peds.2006-0347 PMID: 16951013
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2006Echocardiographic diagnosis and management of bilateral coronary ostial atresia in a patient with pulmonary atresia and intact ventricular septum.. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.PMID: 16825009
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2006Successful implantation of a Berlin heart biventricular assist device in a failing single ventricle. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 1407-1408.Full Text via DOI: 10.1016/j.jtcvs.2006.02.015 PMID: 16733184
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2005Cardiac hemangioma. CIRCULATION. E103-E104.Full Text via DOI: 10.1161/CIRCULATIONAHA.104.487645 PMID: 16116060
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2005Anticoagulation and incidence of late cerebrovascular accidents following the Fontan procedure. PEDIATRIC CARDIOLOGY. 26:56-61.Full Text via DOI: 10.1007/s00246-003-0684-z PMID: 14994183
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2004Interim mortality in pulmonary atresia with intact ventricular septum. ANNALS OF THORACIC SURGERY. 78:1994-1998.Full Text via DOI: 10.1016/j.athoracsur.2004.06.015 PMID: 15561017
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2004Congenital membranous obstruction of the inferior vena cava. ANNALS OF THORACIC SURGERY. 1849-1849.Full Text via DOI: 10.1016/S0003-4975(03)01250-5 PMID: 15511497
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2004Autologous patch angioplasty of the left main coronary artery in a pediatric patient: 7-year follow-up. ANNALS OF THORACIC SURGERY. 77:1457-1459.Full Text via DOI: 10.1016/S0003-4975(03)01262-1 PMID: 15063296
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2004Determinants of mortality and type of repair in neonates with pulmonary atresia and intact ventricular septum. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 127:1000-1008.Full Text via DOI: 10.1016/j.jtcvs.2003.11.057 PMID: 15052196
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2003Rare association of a carotid pseudoaneurysm and coarctation of the aorta.. Interactive cardiovascular and thoracic surgery. 514-6.PMID: 17670109
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2003Tacrolimus dosage requirements after initiation of azole antifungal therapy in pediatric thoracic organ transplantation. PEDIATRIC TRANSPLANTATION. 7:474-478.PMID: 14870897
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2003Traumatic aortic transection in a child with an anomalous right subclavian artery. ANNALS OF THORACIC SURGERY. 76:2087-2089.Full Text via DOI: 10.1016/S0003-4975(03)01178-0 PMID: 14667653
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2003Closed correction of systemic semilunar valve insufficiency in the neonate. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 1650-1652.Full Text via DOI: 10.1016/S0022-5223(03)01016-X PMID: 14666052
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2003Long-term survival after pediatric cardiac transplantation and postoperative ECMO support. ANNALS OF THORACIC SURGERY. 76:843-846.PMID: 12963213
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2003Intrapericardial teratoma in a neonate. ANNALS OF THORACIC SURGERY. 626-626.PMID: 12902126
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2003Interim mortality in infants with systemic-to-pulmonary artery shunts. ANNALS OF THORACIC SURGERY. 76:152-156.PMID: 12842531
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2003Competing perfusion strategies: Effect on microvascular oxygen tension. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 456-456.Full Text via DOI: 10.1067/mtc.2003.247 PMID: 12658183
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2003Intramural left coronary artery associated with right ventricular outflow tract obstruction. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 729-730.Full Text via DOI: 10.1067/mtc.2003.51 PMID: 12658220
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2002Long-term comparison of tacrolimus- and cyclosporine-induced nephrotoxicity in pediatric heart-transplant recipients. AMERICAN JOURNAL OF TRANSPLANTATION. 2:769-773.PMID: 12243498
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2002Case report of combined pediatric heart-lung-liver transplantation. TRANSPLANTATION. 73:1968-1969.PMID: 12131700
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2002Arch reconstruction without circulatory arrest: scientific basis for continued use and application to patients with arch anomalies.. Seminars in thoracic and cardiovascular surgery. Pediatric cardiac surgery annual. 104-15.PMID: 11994870
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2002Successful late reintervention after the arterial switch procedure. ANNALS OF THORACIC SURGERY. 73:88-93.PMID: 11834068
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2001Aortopulmonary size discrepancy is not a contraindication to the pediatric Ross operation. ANNALS OF THORACIC SURGERY. 72:1610-1613.PMID: 11722053
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2001Regional low-flow perfusion provides somatic circulatory support during neonatal aortic arch surgery. ANNALS OF THORACIC SURGERY. 72:401-406.PMID: 11515874
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2001The effect of cytokine gene polymorphisms on pediatric heart allograft outcome. JOURNAL OF HEART AND LUNG TRANSPLANTATION. 20:625-630.PMID: 11404167
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2001Cardiopulmonary transplantation for congenital heart disease in the adult. JOURNAL OF HEART AND LUNG TRANSPLANTATION. 20:297-303.PMID: 11257555
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2001Hypothermic cardiopulmonary bypass alters oxygen/glucose uptake in the pediatric brain. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 121:366-373.PMID: 11174743
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2001Posttransplant diabetes mellitus in pediatric thoracic organ recipients receiving tacrolimus-based immunosuppression. TRANSPLANTATION. 71:252-256.PMID: 11213069
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2000Complete surgical repair of aortic atresia with a normal left ventricle. ANNALS OF THORACIC SURGERY. 70:2145-2147.PMID: 11156139
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2000Management of hepatic venous obstruction after split-liver transplantation.. PEDIATRIC TRANSPLANTATION. 322-7.PMID: 11079274
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2000Endomyocardial biopsy in pediatric heart transplant recipients: a useful exercise? (Analysis of 1,169 biopsies).. PEDIATRIC TRANSPLANTATION. 186-92.PMID: 10933318
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2000Cardiac transplantation in survivors of lymphoma - A multi-institutional survey. TRANSPLANTATION. 69:2112-2115.PMID: 10852607
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2000Management of retroperitoneal arterial injury after heart catheterization in children. ANNALS OF THORACIC SURGERY. 69:1582-1584.PMID: 10881851
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2000Regional low-flow perfusion provides cerebral circulatory support during neonatal aortic arch reconstruction. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 119:331-337.PMID: 10649209
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1999Repair of tetralogy of Fallot in neonates and young infants.. CIRCULATION. II157-61.PMID: 10567296
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1999The effects of cardiopulmonary bypass on remifentanil kinetics in children undergoing atrial septal defect repair. ANESTHESIA AND ANALGESIA. 89:904-908.PMID: 10512263
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1999Regional perfusion of the brain during neonatal aortic arch reconstruction. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 117:1023-1024.PMID: 10220701
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1999Tacrolimus: A cause of hypertrophic cardiomyopathy in pediatric heart transplant recipients?. TRANSPLANTATION PROCEEDINGS. 31:82-83.PMID: 10083017
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1997Lung transplantation for respiratory failure resulting from systemic disease. ANNALS OF THORACIC SURGERY. 64:1630-1634.PMID: 9436547
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1997Cardiac operations in solid-organ transplant recipients. ANNALS OF THORACIC SURGERY. 64:1270-1278.PMID: 9386690
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1997Massive sinus of Valsalva aneurysm presenting with coronary insufficiency. ANNALS OF THORACIC SURGERY. 64:1475-1476.PMID: 9386730
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1996Acute and chronic morbidity differences between muscle-sparing and standard lateral thoracotomies. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 112:1346-1350.PMID: 8911333
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1996Unsuspected lung cancer found in work up for lung reduction operation. ANNALS OF THORACIC SURGERY. 61:174-176.PMID: 8561548
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1995Diagnosis of postpneumonectomy bronchopleural fistula using ventilation scintigraphy. ANNALS OF THORACIC SURGERY. 60:1812-1814.PMID: 8787494
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1993THE EFFECT OF HYPOTENSION AND HYPOXIA ON CHILDREN WITH SEVERE HEAD-INJURIES. JOURNAL OF PEDIATRIC SURGERY. 28:310-316.PMID: 8468638
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1992TUMOR-NECROSIS-FACTOR AND CARDIAC-FUNCTION. JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE. 32:686-692.PMID: 1613827
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1987SMALL-BOWEL INFARCTION AND DEATH FROM PRIMARY MESENTERIC VENOUS THROMBOSIS. AMERICAN JOURNAL OF EMERGENCY MEDICINE. 126-129.PMID: 3828014
Background
Full Name
- Frank Pigula, MD
Education
- University Of Vermont; Boston Children's Hospital; University Health Center of Pittsburgh
Residency
- University Health Center of Pittsburgh, PA
Fellowship
- Boston Children's Hospital, MA
Board Certification
- American Board of Thoracic Surgery
Contact
primary email
- Research.Institute@AdventHealth.com